18F-FDG PET腹部阳性病灶PET/CT与PET/MR图像特征的对比分析  

Comparative Analysis of Image Characteristics of 18F-FDG PET-Positive Abdominal Lesions on PET/CT and PET/MR

作　　者：唐勇进[1] 程勇[1] 徐浩[1] 尚靖杰[1] 凌雪英[1] TANG Yongjin;CHENG Yong;XU Hao;et al(Department of Nuclear Medicine,The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province 510630, P. R. China)

机构地区：[1]暨南大学附属第一医院核医学科

出　　处：《临床放射学杂志》2018年第3期436-440,共5页Journal of Clinical Radiology

摘　　要：目的比较上腹部氟代脱氧葡萄糖（^（18）F-FDG）正电子发射断层显像（PET）阳性病灶在PET/CT和PET/MR上的图像特征,为PET/MR在腹部的临床应用提供依据。方法同时接受^（18）F-FDG PET/CT-MRI多模式扫描的患者81例,MRI扫描序列包括肝脏快速容积采集（LAVA）序列、轴位T_2WI及轴位DWI（b值为0和800 s/mm^2）。评估符合参考标准的PET阳性病灶在PET/CT、PET/MR上的图像质量、病灶清晰度、最大病灶长径、病灶特征等。结果 81例患者共计176个腹部PET阳性病灶,这些病灶在PET/CT及PET/MR上的图像质量、最大病灶长径差异无统计学意义（P〉0.05）。PET/MR显示腹部阳性病灶的清晰度优于PET/CT,特别是对肝脏阳性病灶（P〈0.001）,对腹部肝脏以外的阳性病灶则差异无统计学意义（P〉0.05）。结论 PET/MR对肝脏病变的显示较PET/CT有明显优势,对肝脏外的腹部病变的显示和PET/CT相似。Objective To compare image characterizations of ^（18）F-FDG PET-positive abdominal lesions on PET/CT and on PET/MR. Methods A total of 81 patients underwent routine whole-body ^（18）F-FDG PET/CT and followed by MRI on a trimodality PET/CT-MRI system. MRI covered the upper abdomen with a sequence combination of liver acquisition with volume acceleration（ LAVA） sequence,T_2-weighted images（ T_2 WI） with fat-suppression,diffusion-weighted imaging（ DWI） with b-values of 0,800 s/mm^2. According to the reference standard,two readers analyzed PET-positive lesions data sets by PET/CT and PET/MR regarding lesion localization,conspicuity,size and additional relevant information for characterization. Results 81 patients had 176 PET-positive lesions at the time of the examination. No significant difference between PET/MR and PET/CT was found regarding anatomical lesion localization and size（ P 0. 05）. The conspicuity of liver PET-positive lesions in PET/MR performed significantly better than PET/CT（ P 0. 001）,whereas no difference was found for extrahepatic PET-positive lesions（ P 0. 05）. Conclusion PET/MR shows obvious advantages than PET/CT in abdominal liver lesions,performed similarly in extrahepatic lesions.

关 键 词：PET/MR PET/CT 腹部 多模式影像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R817.4[医药卫生—诊断学]