咪唑并[1,2-a]吡啶C-3位C—H官能团化研究进展  

Progress in C—H Bond Functionalization on C-3 Position of Imidazo[1,2-a]pyridines

作　　者：金城安 徐庆 冯高峰[1] 金阳[1,2] 张连阳 Jin Cheng＇an;Xu Qing;Feng Gaofeng;Jin Yang;Zhang Lianyang(College of Chemistry and Chemical Engineering, Shaoxing University, Shaoxing 312000;Key Laboratory of Clean Dyeing and Finishing Technology of Zhejiang Province, Shaoxing University, Shaoxing 312000;College of Textile and Garment, Shaoxing University, Shaoxing 312000)

机构地区：[1]绍兴文理学院化学化工学院,绍兴312000 [2]绍兴文理学院浙江省清洁染整技术研究重点实验室,绍兴312000 [3]绍兴文理学院纺织服装学院,绍兴312000

出　　处：《有机化学》2018年第4期775-790,共16页Chinese Journal of Organic Chemistry

基　　金：绍兴文理学院校级科研(No.2016LG1011)资助项目~~

摘　　要：3-取代咪唑并[1,2-a]吡啶类化合物是一类重要的含氮稠环化合物,在医药、材料等领域具有广泛的应用价值.C-3位C—H官能团化是构建3-取代咪唑并[1,2-a]吡啶类化合物的简单有效方法.按咪唑并[1,2-a]吡啶C-3位的成键类型(C—C、C—S/Se、C—N/P)进行分类,主要介绍了近几年来咪唑并[1,2-a]吡啶等氮杂稠环化合物C-3位C—H官能团化反应进展,并对今后发展作出了展望.3-Substituted imidazo[1,2-a]pyridines are important N-fused heterocycles with extensive application value in medicine, materials and other fields. C（3）--H bond functionalization strategy was a simple and effective way to build 3-substituted imidazo[ 1,2-a]pyridines. The recent advances of the access to 3-substituted imidazo[ 1,2-a]pyridines according to the type of bonding （C--C, C--S/Se, C--N/P） on C-3 position are briefly summarized, and a prospect for the future develop- ment is made.

关 键 词：3-取代咪唑并[1 2-a]吡啶 C-H官能团化 C-3位 

分 类 号：O626[理学—有机化学]