Iodine-mediated regioselective hydroxyselenenylation of alkenes:Facile access to β-hydroxy selenides  

作　　者：Xian-Long Wang Hong-Jie Li Jie Yan 

机构地区：[1]College of Chemical Engineering, Zhejiang University of Technology

出　　处：《Chinese Chemical Letters》2018年第3期479-481,共3页中国化学快报（英文版）

摘　　要：In the presence of molecular iodine, the reaction of alkenes with diselenides proceeds efficiently under air and at room temperature in mixed solvent MeCN/H2O, which affording β-hydroxy selenides with high regioselectivity and in good to excellent yields. This iodine-mediated vicinal difunctionalization of alkenes requires mild reaction conditions and is a simple procedure, which extends the synthetic application of molecular iodine in organic synthesis.In the presence of molecular iodine, the reaction of alkenes with diselenides proceeds efficiently under air and at room temperature in mixed solvent MeCN/H2O, which affording β-hydroxy selenides with high regioselectivity and in good to excellent yields. This iodine-mediated vicinal difunctionalization of alkenes requires mild reaction conditions and is a simple procedure, which extends the synthetic application of molecular iodine in organic synthesis.

关 键 词：β-Hydroxy selenide Hydroxyselenenylation Diselenide Alkene I2 

分 类 号：O621.25[理学—有机化学]