2-Amino homopropargyl alcohols from the highly regioselective Ag_2CO_3-catalyzed nucleophilic openings of alkynyl epoxides by amines  

作　　者：Jianlin Yang Ming Zhang Peng Wang Wenjuan Liu Ruwei Shen 

机构地区：[1]State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University [2]College of Materials Science and Engineering, Nanjing Tech University

出　　处：《Chinese Chemical Letters》2018年第3期524-526,共3页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(No. 21302095);Research Fund for the Doctoral Program of Higher Education of China(No. 20133221120003);Jiangsu Provincial NSFC(Nos. BK20130945, BK20130924);Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP);Nanjing Tech University for financial support

摘　　要：The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,

关 键 词：Alkynyl epoxide Ring opening Silver catalysts Regioselectivity Amino alcohol 

分 类 号：O621.251[理学—有机化学]