Relationships between Gene Structure and Genome Instability in Flowering Plants  

作　　者：Jeffrey L. Bennetzen Xuewen Wang 

机构地区：[1]State Key Laboratory of Tea Plant Biology and Utilization/Key Laboratory of Tea Biology and Processing, Ministry of Agriculture, Anhui Agricultural University, Hefei,Anhui 230036, People's Republic of China [2]Department of Genetics, University of Georgia, Athens, GA 30602, USA

出　　处：《Molecular Plant》2018年第3期407-413,共7页分子植物（英文版）

摘　　要：Flowering plant （angiosperm） genomes are exceptional in their variability with respect to genome size, ploidy, chromosome number, gene content, and gene arrangement. Gene movement, although observed in some of the earliest plant genome comparisons, has been relatively underinvestigated. We present here- in a description of several interesting properties of plant gene and genome structure that are pertinent to the successful movement of a gene to a new location. These considerations lead us to propose a model that can explain the frequent success of plant gene mobility, namely that Small Insulated Genes Move Around （SlGMAR）. The SIGMAR model is then compared with known processes for gene mobilization, and predic- tions of the SIGMAR model are formulated to encourage future experimentation. The overall results indicate that the frequent gene movement in angiosperm genomes is partly an outcome of the unusual properties of angiosperm genes, especially their small size and insulation from epigenetic silencing.Flowering plant （angiosperm） genomes are exceptional in their variability with respect to genome size, ploidy, chromosome number, gene content, and gene arrangement. Gene movement, although observed in some of the earliest plant genome comparisons, has been relatively underinvestigated. We present here- in a description of several interesting properties of plant gene and genome structure that are pertinent to the successful movement of a gene to a new location. These considerations lead us to propose a model that can explain the frequent success of plant gene mobility, namely that Small Insulated Genes Move Around （SlGMAR）. The SIGMAR model is then compared with known processes for gene mobilization, and predic- tions of the SIGMAR model are formulated to encourage future experimentation. The overall results indicate that the frequent gene movement in angiosperm genomes is partly an outcome of the unusual properties of angiosperm genes, especially their small size and insulation from epigenetic silencing.

关 键 词：epigenetic silencing gene insulators gene movement illegitimate recombination inaccurate DNA break repair transposon mobilization 

分 类 号：Q343.2[生物学—遗传学] Q754