针灸治疗原发性失眠的随机对照试验  

Acupuncture Treatment of Primary Insomnia Based on Regulating Du Meridian and Calming Mind: A Randomized Controlled Trial

作　　者：殷萱 吴焕淦[2] 勾明会 汪司右[2] 徐世芬[1] Yin Xuan;Wu Huangan;Gou Minghui;Wang Siyou;Xu Shifen(Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200071, China;Acupuncture and Meridian Research Institute, Shanghai University of Traditional Chinese Medicine, Shanghai 200030, China;Beijing Fengtai Hospital of Traditional Chinese and Western Medicine, Beijing 100072, China)

机构地区：[1]上海中医药大学附属上海市中医医院,上海200071 [2]上海中医药大学针灸经络研究所,上海200030 [3]北京丰台区中西医结合医院,北京100072

出　　处：《世界科学技术-中医药现代化》2018年第2期198-202,共5页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家科学技术部973计划项目(2009CB522900):灸法的基本作用原理与应用研究规律;负责人:吴焕淦;国家科学技术部973计划项目(2015CB554500):基于临床的灸法作用机理研究;负责人:吴焕淦;上海市卫计委中医药科研基金项目(2010L036A):原发性失眠针刺优化方案及影响疗效共性技术的临床评价;负责人:徐世芬

摘　　要：目的:评价调督安神法针灸治疗原发性失眠的临床疗效及安全性。方法:本研究采用患者随机对照试验设计,将72例原发性失眠患者按1∶1比例分为治疗组和对照组。治疗组以调督安神法为治疗原则进行针灸治疗,要求得气,取穴百会、神庭、印堂、神门、安眠、三阴交;对照组为假针灸治疗,假针灸针不刺破皮肤,取穴同治疗组。两组每次均治疗30 min,每周3次,连续治疗4周。分别在治疗前、治疗2周、治疗4周以及治疗结束后2周、4周随访时对患者进行失眠严重程度指数(ISI)、焦虑自评量表(SAS)以及抑郁自评量表(SDS)的评估,观察并记录针灸的不良反应。结果:治疗组完成32例,脱落4例;对照组完成30例,脱落6例。与治疗前相比,两组的ISI评分在治疗后及随访时有显著性差异(P<0.01);与对照组相比,治疗组在治疗4周、治疗结束后2周、4周随访时评分差异有统计学意义(P<0.05),但在治疗2周时差异无统计学意义(P>0.05)。与对照组相比,治疗组的SAS及SDS评分在治疗4周、治疗结束后2周、4周随访时有显著性差异(P<0.01,P<0.05),但在治疗2周时差异无统计学意义(P>0.05)。两组针灸疗法不良事件发生率比较,差异无统计学意义(P>0.05)。结论:调督安神法针灸方案治疗原发性失眠临床疗效显著,安全性高。This study was aimed to evaluate the efficacy and safety of acupuncture based on regulating Du meridian andcalming mind in the treatment of primary insomnia. A patient-blinded, randomized controlled trial was designed. A totalof 72 primary insomnia patients were randomly divided into the treatment group and the control group. Patients in thetreatment group received acupuncture with deqi sensation at DU-20 Baihui, DU-24 Shenting, EX Yintang, HT-7 Shenmen, EX Anmian and SP-6 Sanyinjiao. Patients in the control group received sham acupuncture without needleinsertion at the same acupoints. All sessions of acupuncture treatment were conducted for 30 minutes each time, 3 timesa week, for 4 consecutive weeks. The insomnia severity index（ISI）, anxiety self-rating scale（SAS） and depression self-rating scale（SDS） were measured before treatment, 2-week treatment, 4-week treatment, 2 weeks and 4 weeks aftertreatment. Adverse reactions of acupuncture treatment were also recorded. The results showed that the treatment groupcompleted 32 cases, 4 cases off; the control group completed 30 cases, 6 cases off. Compared with those before treatment,the ISI scores of both groups were significantly different after treatment and at follow-up（P〉0.01）. Compared with thecontrol group, there was statistical difference in the treatment group at 4-week treatment, 2 weeks and 4 weeks aftertreatment（P〈0.05）. However, there was no statistical significance at 2-week treatment（P〈0.05）. Compared with thecontrol group, there were significant differences on SAS and SDS scores of the treatment group at 4-week treatment, 2 weeks and 4 weeks after treatment（P〈0.01, P〈0.05）. However, there was no statistical significance at 2-weektreatment（P〉0.05）. There was no statistical significance on the comparison of adverse reactions of acupuncturetreatment between two groups（P〉0.05）. It was concluded that acupuncture treatment based on regulating Du meridianand calming mind was an effective and safe therapy for pr

关 键 词：调督安神法 针灸 原发性失眠 失眠严重指数 随机对照试验 

分 类 号：R246[医药卫生—针灸推拿学]