养阴清肺汤联合西药治疗阴虚燥热型慢性支气管炎急性发作临床观察  

Clinical Observation of Yangyin Qingfei Tang Combined with Western Medicine for Chronic Bronchitis in Acute Attack of Yin Deficiency and Dryness heat Type

作　　者：葛祥 GE Xiang

机构地区：[1]嘉兴市第二医院呼吸科,浙江嘉兴314000

出　　处：《新中医》2018年第3期71-74,共4页New Chinese Medicine

摘　　要：目的:观察养阴清肺汤联合西药治疗阴虚燥热型慢性支气管炎急性发作的临床疗效。方法:将82例阴虚燥热型慢性支气管炎急性发作患者随机分为对照组与研究组,每组41例。对照组采用常规西药治疗,研究组在常规西药治疗基础上加用养阴清肺汤。比较2组临床总有效率、症状体征缓解时间,观察2组治疗前后白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)水平的变化。结果:研究组治疗总有效率92.68%,对照组治疗总有效率75.61%,2组比较,差异有统计学意义(P<0.05)。研究组咳嗽、咯痰、喘息及肺部啰音的缓解时间均短于对照组,差异均有统计学意义(P<0.05)。治疗前,2组IL-6及TNF-α水平比较,差异均无统计学意义(P>0.05)。治疗后,2组IL-6及TNF-α水平均较治疗前下降,差异均有统计学意义(P<0.05);研究组的IL-6及TNF-α水平均低于对照组,差异均有统计学意义(P<0.05)。结论:养阴清肺汤联合西药治疗阴虚燥热型慢性支气管炎急性发作疗效显著。Objective：To observe the clinical effect of Yangyin Qingfei tang combined with western medicine for chronic bronchitis in acute attack of yin deficiency and dryness heat type. Methods：Divided 82 cases of patients with chronic bronchitis in acute attack of yin deficiency and dryness heat type randomly into the control group and the study group,41 cases in each group. The control group was given routine western medicine for treatment,while the study group was additionally given Yangyin Qingfei tang based on the treatment of western medicine. Compared the clinical total effective rate and remission time of symptoms and signs in two groups. Observed level changes of interleukin-6（IL-6） and tumor necrosis factor（TNF-α） before and after treatment. Results：The total effective rate was 92.68% in the study group and was 75.61%in the control group,the difference being significant（P〈0.05）. The remission time of cough,expectoration,asthma and lung rales in the study group was all shorter than that in the control group,the difference being significant（P〈0.05）. Before treatment,there was no significant difference being found in the comparison of levels of IL-6 and TNF-α in two groups（P〈0.05）. After treatment, levels of IL-6 and TNF-ɑ in two groups were decreased when compared with those before treatment,differences being significant（P〈0.05）. Levels of IL-6 and TNF-α in the study group were lower than those in the control group,differences being significant（P〈0.05）. Conclusion：The therapy of Yangyin Qingfei tang combined with western medicine has a significant clinical effect in treating chronic bronchitis in acute attack of yin deficiency and dryness-heat type.

关 键 词：慢性支气管炎 急性发作 阴虚燥热 中西医结合疗法 养阴清肺汤 白细胞介素-6(IL-6) 肿瘤坏死因子-α(TNF-α) 

分 类 号：R562.21[医药卫生—呼吸系统]