对1395个夫精人工授精治疗周期的临床分析  

Analysis of the treatment cycle of 1395 artificial insemination by husband

作　　者：李道云[1] 高红艳[1] 孔祥 

机构地区：[1]常州市第一人民医院,江苏常州213000

出　　处：《实用妇科内分泌电子杂志》2018年第5期31-33,共3页Electronic Journal of Practical Gynecological Endocrinology

基　　金：江苏省妇幼健康科研资助项目(F201724);江苏省妇幼健康重点人才培养

摘　　要：目的探讨不同排卵方案、子宫内膜厚度及类型、不同授精时机对宫腔内夫精人工授精(AIH)的临床妊娠率(CPR)的影响。方法选择2009年至2016年度因不孕症原因至苏北人民医院进行AIH治疗的1395个周期,根据排卵方案、子宫内膜厚度及类型、授精时机的不同分别进行分组,依次比较自然周期与促排卵周期、子宫内膜厚度及类型、不同授精时机的AIH的CPR。结果 (1)自然周期组与促排卵周期组的女方年龄比较,差异有统计学差意义(P<0.05),促排卵周期组年龄高于自然周期组;两组治疗周期的CPR比较,无统计学意义(P>0.05);(2)子宫内膜厚度及类型各组间CPR比较无统计学意义(P>0.05);(3)排卵前人工授精、排卵后人工授精、排卵前后双次人工授精三组的CPR比较,差异有统计学意义(P<0.05),排卵后单次人工授精的CPR高于排卵前单次人工授精。结论年龄较大的女性建议行促排卵方案,但不影响CRP;子宫内膜厚度及类型不影响CRP;排卵后单次人工授精,可提高夫精人工授精的CRP。Objective To evaluate the impacts of different ovulation programs of treatment, different thickness and types of endometrium and different timing of insemination on the clinical pregnancy rate of artificial insemination by husband. Methods According to different ovulation schemes, endometrial thickness and type, and timing of insemination, the data was divided into natural cycle group and ovulation cycle group, endometrial thickness group and type group, and different timing of insemination group, in order to compare the difference of the clinical pregnancy rate of artificial insemination by husband between natural cycle and ovulation cycle, endometrial thickness and type, and timing of different insemination in turn. Results(1)There is a statistically significant difference in the age of the women in the natural cycle group and the ovulation cycle group(P<0.001). The average age of women in the ovulation cycle group is larger than that of the natural cycle group.(2)The clinical pregnancy rate was not significantly different among the groups of endometrial thickness and type(P>0.05);(3)The clinical pregnancy rate of a single artificial insemination after ovulation is higher than single insemination before ovulation, and the difference was statistically significant(P<0.05). Conclusion(1) The older women will affect the normal ovulation; single artificial insemination after ovulation is recommended, because it can significantly improve the clinical pregnancy rate of intrauterine insemination.

关 键 词：人工授精 临床妊娠率 授精时机 

分 类 号：R711.6[医药卫生—妇产科学]