超声应变率成像评估急性胰腺炎患者左心收缩功能及其与CTSI的相关性  

Correlation of left ventricular systolic function evaluated by strain rate imaging with computed tomography severity index in patients with acute pancreatitis

作　　者：史涛 王喻 李闯 郑惟 Tao Shi;Yu Wang;Chuang Li;Wei Zheng(Department of Radiology, the First People＇s Hospital of Yuhang District of Zhejiang Province, Hangzhou 311100, Zhejiang Province, China;Department of Ultrasonography, Zhejiang Hospital Hangzhou 310013, Zhejiang Province, Chin;Department of Radiology, Zhejiang Hospital, Huzhou 310013, Zhejiang Province, China;Department of Radiology, the First People＇s Hospital of Deqing County, Hangzhou 313200, Zhejiang Province, Chin)

机构地区：[1]杭州市余杭区第一人民医院放射科,浙江省杭州市311100 [2]浙江医院超声科,浙江省杭州市310013 [3]浙江医院放射科,浙江省杭州市310013 [4]德清县人民医院超声科,浙江省湖州市313200

出　　处：《世界华人消化杂志》2018年第8期524-529,共6页World Chinese Journal of Digestology

摘　　要：目的运用超声应变率成像技术(strain rate imaging,SRI)评估急性胰腺炎(acute pancreatitis,AP)患者的左心收缩功能,并探讨其与CT严重度指数(computed tomography severity index,CTSI)评分的相关性.方法选取浙江医院收治的74例AP患者作为研究对象,根据不同严重程度分为:水肿型AP组(A组,43例)和出血坏死型AP组(B组,31例),另选45例健康体检者作为正常组.所有研究对象均接受SRI检查、CT检查及血浆脑钠肽前体(brain natriuretic peptide precursor,BNP-pro)水平测定,记录相关参数作比较分析.结果B组CTSI评分明显高于A组,差异有统计学意义(P<0.05);B组血浆BNP-pro水平明显高于A组及正常组,而左心射血分数(left ventricular ejective fraction,LVEF)、二尖瓣口水平舒张期血流频谱E峰与A峰比值(mitral e peak and a peak ratio,E/A)、左心室平均收缩期峰值应变率(mean of systolic strain rate peak,mSRs)均明显低于A组及正常组,差异均有统计学意义(均P<0.05);A组血浆BNP-pro水平明显高于正常组,而mSRs明显低于正常组,差异均有统计学意义(均P<0.05);AP患者的mSRs分别与血浆BNP-pro水平、CTSI评分呈负相关性(r=-0.825,r=-0.775,均P<0.05).结论SRI能准确评估AP患者左心收缩功能变化,且与CTSI具有良好相关性,有助于评估患者的病情严重程度,为临床治疗提供参考.AIM To evaluate the left ventricular systolic function in patients with acute pancreatitis（AP）by strain rate imaging（SRI）,and to analyze its correlation with computed tomography severity index（CTSI）.METHODS Seventy-four cases of AP treated at the Zhejiang Hospital were divided into two groups according to the severity：edematous pancreatitis group（group A,43 cases）and hemorrhagic necrosis pancreatitis group（group B,31 cases）.At the same time,45 cases of healthy persons were selected as a normal group.All the subjects underwent SRI,CT,and measurement of plasma brain natriuretic peptide precursor（BNP-pro）levels,and these parameters were compared between different groups.The correlation between these parameters was also analyzed CTSI score in group B was significantly higher than that in group A（P 〈 0.05）.Plasma BNP-pro level in group B was significantly higher than that in group A and the normal group.Left（LVEF）,mitral e peak and a ventricular ejective fraction peak ratio（E/A）,and mean of systolic strain rate peak（mSRs）were significantly lower in group B than in group A and the normal group（P 〈 0.05）.Plasma BNP-pro level in group A was significantly higher than that in the normal group,while mSRs was significantly lower than that in the normal group（P 〈 0.05）.mSRs was negatively correlated with plasma BNP-pro level and CTSI score in patients with AP（r =-0.825,r =-0.775,P 〈 0.05）.CONCLUSION SRI can accurately evaluate left ventricular systolic function in patients with AP,and has a good correlation with CTSI score,which can help to assess the severity of AP.

关 键 词：超声心动描记术 应变率 急性胰腺炎 心功能 CT严重度指数 

分 类 号：R445.1[医药卫生—影像医学与核医学]