受孕季节与孕妇异常增重及异常出生体重的关系  

The relationship between different conception time and gestational weight gain or abnormal birth weight

作　　者：赵薇[1] 董宇琪 肖艳慧 黄爱群[1] 王琳琳[2] ZHAO Wei;DONG Yuaqi;XIAO Yanhui;HUANG Aiqun;WANG Linlin(National Center for Women and Children＇s Health, China CDC , Beijing , 100081;Department of Epidemiolo- gy and Biostatistics, School of Public Health, Peking University Health Science Center, Institute of Reproductive and Child Health, Ministry of Health Key Laboratory of Reproductive Health)

机构地区：[1]中国疾病预防控制中心妇幼保健中心,北京100081 [2]北京大学公共卫生学院流行病与卫生统计学系、北京大学生育健康研究所、卫生部生育健康重点实验室

出　　处：《中国计划生育学杂志》2018年第4期244-247,259,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨不同受孕季节与孕妇异常增重及异常出生体重的关系。方法:选取2013年10月—2015年9月全国6省12县加入中国疾病预防控制中心妇幼保健中心孕产妇及新生儿健康监测系统的29 711名孕产妇与其足月产新生儿为研究对象。使用多因素logistic回归分析不同受孕季节与孕期异常增重及异常出生体重的关系。调整因素包括孕妇年龄、民族、教育程度、孕前体质量指数(BMI)、地区、胎儿性别。结果:巨大儿发生率为5.9%,足月小样儿发生率为1.3%。受孕季节在秋季减小了巨大儿的发病风险,以春季作为参照组,受孕季节在秋季巨大儿的发生风险的调整OR值为0.76(95%CI 0.66~0.88)。受孕季节在秋、冬季降低了体重增长过速的发生风险,以春季作为参照组,夏季、秋季和冬季受孕者体重增长过速的发生风险调整OR值分别为0.84(95%CI 0.76~0.91)、0.46(95%CI0.42~0.50)和0.56(95%CI 0.51~0.61)。结论:异常出生体重季节性变化主要与孕妇孕期体重增长季节性变化有关。秋季受孕的孕妇孕期体重增长过速发生率较低,并且新生儿中巨大儿发生率较其他季节低,提示具有巨大儿发生高危因素的备孕妇女可选择在秋季妊娠。Objective：To explore the relationship between different conception time and gestational weight gain or abnormal birth weight.Methods：From October 2013 to September 2015,29711 maternal and newborn who recorded in 12 counties of 6 provinces joining the health care systerm of national center for women and children＇s health,China CDC were selected.The multiple logistic regression analysis was used to survey the correlation between different conception time and gestational weight gain or abnormal birth weight.Adjustment factors included maternal age,education,pre-pregnant BMI,district,and fetal sex.Results：The incidence of macrosomia was 5.9 %,while incidence of small for gestational age of infants was 1.3%.During the autumn,the onset of pregnancy decreased the risk of macrosomia,when compared to that during the spring,the adjusted OR（95 % CI）of incidence of macrosomia during the autumn Was 0.76 and 0.66-0.88.The onset of pregnancy during the autumn and winter reduced the risk of weight gain too much of pregnant women.When compared to that during the spring,the adjusted OR（95% CI）of incidence of weight gain of pregnant women during the summer,the autumn,and the winter were 0.84（0.76-0.91）,0.46（0.42-0.50）and 0.42（0.51-0.61）,respectively.Conclusion：The seasonal pattern in abnormal birth weight was related to seasonality of gestational weight gain.Both the rate of gestational weight gain and the incidence of macrosomia were lower when women who become to pregnancy in autumn,which has suggested that pregnant women with high risk factors of macrosomia maybe choose to conception in fall.

关 键 词：受孕时间 孕期体重变化 出生体重 

分 类 号：R173[医药卫生—妇幼卫生保健]