1720例不同健康状态及年龄梯度人群脉图特征研究  

Research on pulse graph characteristics of 1720 cases with different health status and age gradient

作　　者：崔骥[1] 屠立平 张建峰[1] 胡晓娟 黄景斌[1] 王广丽[4] 王唯坚[5] 张志枫[1] 许家佗[1] CUI Ji;TU Liping;ZHANG Jianfeng;HU Xiaojuan;HUANG Jingbin;WANG Guangli;WANG Weijian;ZHANG Zhifeng;XU Jiatuo(School of Basic Medical Science, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Institute of Disciplinary Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;Shanghai Innovation Center of TCM Health Service, Shanghai 201203, China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji＇nan 250014, China;Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China)

机构地区：[1]上海中医药大学基础医学院,上海201203 [2]上海中医药大学交叉科学研究院,上海201203 [3]上海中医健康服务协同创新中心,上海201203 [4]山东中医药大学附属医院,山东济南250014 [5]上海中医药大学附属曙光医院,上海201203

出　　处：《上海中医药杂志》2018年第4期15-23,共9页Shanghai Journal of Traditional Chinese Medicine

基　　金：科技部"十三五"重点研发计划项目(2017YFC1703300);科技部"十二五"国家科技支撑计划项目(2012BAI37B06);国家自然科学基金项目(81373556);上海市教委曙光计划项目(12SG36);上海市卫计委中医药科技创新项目(ZYKC201602003);上海中医药大学预算内项目(2016YSN02);上海中医药大学课程建设项目(SHUTCMKCJSYB2017080)

摘　　要：目的采用自行研制的PDA-1型脉诊仪采集非疾病人群脉图,分析不同健康状态、不同年龄梯度的脉图特征,为中医脉诊学的临床应用研究提供参考。方法采集1 720例非疾病人群的基本信息及脉图信息,以自主研制的"H20问卷"进行健康状态判别,分析不同年龄梯度健康人群、不同年龄梯度亚健康人群、同年龄梯度内健康与亚健康人群的脉图差异及特征信息。结果 (1)1 720例非疾病人群中,健康人群730例,亚健康人群990例。(2)健康组与亚健康组比较,h_5值显著降低(P<0.01),t_4、t_5、h_3/h_1、h_4/h_1、t_4/t_5、w_1/t、w_2/t值显著升高(P<0.05,P<0.01)。(3)不同年龄梯度健康人群脉图参数比较,40-49岁年龄梯度与≥50岁年龄梯度脉图参数差异无统计学意义(P>0.05),而与<30岁年龄梯度、30-39岁年龄梯度有差异,具体表现在h_5值显著降低(P<0.01),h_3、h_4、t_4、h_3/h_1、w_1/t等值显著升高(P<0.05,P<0.01)。(4)不同年龄梯度亚健康人群脉图参数比较结果显示,随着年龄的增加,h_5值显著降低(P<0.01),t_1、t_4、t_4/t_5值显著升高(P<0.05,P<0.01)。(5)同年龄梯度健康与亚健康人群脉图参数比较结果显示,在<30岁、30-39岁年龄梯度内,亚健康人群脉图参数h_5值显著降低(P<0.05),<30岁年龄梯度t_4、h_3/h_1、t_4/t_5、w_1/t值显著升高(P<0.05,P<0.01);30-39岁年龄梯度t_4、h_4/h_1值显著升高(P<0.05,P<0.01);40-49岁、≥50岁年龄梯度内及两个年龄梯度间比较,健康人群与亚健康人群脉图参数差异无统计学意义(P>0.05),较<30岁、30-39岁年龄梯度,h_5逐渐降低。结论健康人群与亚健康人群的脉图有差异,相同年龄段不同健康状态人群之间的脉图也有差异,主要表现在h_5、h_3/h_1、w_1/t等指标;研究结果提示,亚健康状态人群的左心室射血功能和大动脉顺应性降低,动脉血管弹性降低,外周阻力增加,脉象偏弦。脉图可以作为一种评估健康状态的客观依据。Objective To analyze the pulse graph characteristics of non-disease population with different health status and age gradient based on self-developed pulse diagnosis instrument（ PDA-1）,and provide reference for the research on clinical application of Chinese medical pulse diagnosis. Methods The basic information and pulse graph of 1 720 non-disease subjects were collected. The health status of each case was evaluated by self-developed H20 questionnaire. The differences on pulse graphs and characteristic information were analyzed in healthy subjects with different age gradient,sub-healthy subjects with different age gradient and healthy and subhealthy subjects with same age. Results（1）Among the 1 720 non-disease cases,there were 730 healthy cases and 990 sub-healthy cases.（2）Compared with the healthy group,the value of h5 was decreased significantly in the sub-healthy group（ P〈0.01）,and the values of t4,t5,h3/h1,h4/h1,t4/t5,w1/t and w2/t were increased significantly（ P〈0.05,P〈0.01）.（3）In healthy subjects,there were no statistically significant differences on the pulse graph parameters between people of age from 40 to 49 year-old and those equal or more than 50 year-old gradient（ P〉0.05）. There were statistically significant differences on the pulse graph parameters between people of age from 40 to 49 year-old and those less than 30 year-old or those of age from 30-39 year-old. To be specific,the value of h5 was decreased significantly（ P〈0.01） and the values of h3,h4,t4,h3/h1,w1/t were increased significantly（ P〈0.05,P〈0.01） in the pulse graph of subjects with age from 40 to 49 year-old.（4）In sub-healthy subjects,with the increasing age,the value of h5 was decreased significantly（ P〈0.01） and the values of t1,t4,t4/t5 were significantly increased（ P〈0.05,P〈0.01）.（5）For the comparison between the healthy and sub-healthy subjects with the same age gradient,in the age of 30 and 30 to 39 year-old,the value of h5 was decreased significantly in sub-h

关 键 词：非疾病人群 年龄梯度 健康状态 亚健康 脉图特征 

分 类 号：R241[医药卫生—中医诊断学]