术后正负性情绪对女性乳腺癌患者预后的影响  

The Effect of Positive and Negative Affect on Prognosis among Women with Breast Cancer

作　　者：李诗晨[1] 朱熊兆[1] 贺婧 李玲艳[1] 王瑜萍[1] 李敏洪[2] 郑泓[1] 杨玉玲[1] LI Shi-chen;ZHU Xiong-zhao;HE Jing;LI Ling-yan;WANG Yu-ping;LI Min-hong;ZHENG Hong;YANG Yu-ling(Medical Psychological Center, The Second Xiangya Hospital, Central South University, Changsha 410011, China;Department of Neurosurgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China)

机构地区：[1]中南大学湘雅二医院医学心理中心,长沙410011 [2]中南大学湘雅二医院神经外科,长沙410011

出　　处：《中国临床心理学杂志》2018年第2期383-386,共4页Chinese Journal of Clinical Psychology

基　　金：国家"十一五"科技支撑计划课题基金(2009BAI77B06)资助

摘　　要：目的:探讨术后正负性情绪对女性乳腺癌患者预后的影响。方法:使用正负性情绪量表对277例女性乳腺癌患者术后一周的正、负性情绪进行评定,并收集患者一般人口学资料和临床病理资料。5年后,采用电话随访了解患者生存情况。采用Kaplan-Meier法计算生存率,采用Log-rank检验及Cox回归分析分别对分类变量和连续变量进行预后因素分析。结果:乳腺癌患者5年生存率为75.45%。淋巴结分期、长期居住地、正性情绪、负性情绪均为乳腺癌预后的影响因素(均P<0.001)。但控制淋巴结分期和长期居住地后,正性情绪仍显著影响患者预后(RR=0.756;95%CI 0.701-0.815;P<0.001),而负性情绪对预后的影响不再显著。结论:术后情绪影响乳腺癌预后,其中正性情绪对预后的影响比负性情绪更加重要。Objective： To examine whether and how post-surgery positive affect and negative affect influence the prognosis of women with breast cancer. Methods： In total, 277 women with breast cancer completed a form for socio-demographic and clinical information as well as the Chinese version of Positive and Negative Affect Scale. Kaplan-Meier method was conducted for survival analysis. Log-rank test and Cox regression analysis were conducted respectively for categorical variable and continuous variable. Results： The five-year survival rate for patients was 75.45%. The results of Log-rank test showed that there were significant differences between survival and non-survival patients in AJCC nodes pathologic sta- tus and long-term residence place（all P〈0.01）. The results of Cox regression analysis showed that post-surgery positive affect significantly predicted prognosis of women with breast cancer after controlling significant prognostic factors in univariate analysis（tilt=0.756; 95%CI 0.701-0.815; P〈0.001） while the influence of negative affect was not significant. Conclusion： Post-surgery emotion influences the prognosis of women with breast cancer. Notably, the influence of positive affect on prognosis of breast cancer is greater in comparison with negative affect.

关 键 词：乳腺癌 正性情绪 负性情绪 预后 生存分析 

分 类 号：R395.6[哲学宗教—心理学]