泻青丸合升降散治疗肝郁化火型失眠症伴焦虑疗效观察  

Clinical Observation of Xieqing Pills Combined with Shengjiang Powder for Insomnia and Anxiety of Syndrome of Liver Depression Transforming into Fire

作　　者：陈星宇 蔡伟彬 林家羽 余恒旺 CHEN Xingyu;CAI Weibin;LIN Jiayu;YU Hengwang

机构地区：[1]广州中医药大学,广东广州510405 [2]广州中医药大学附属茂名中医院,广东茂名525000

出　　处：《新中医》2018年第4期63-66,共4页New Chinese Medicine

摘　　要：目的:观察泻青丸合升降散治疗肝郁化火型失眠症伴焦虑的临床疗效。方法:将80例肝郁化火型失眠症伴焦虑患者随机分为观察组和对照组,每组40例。对照组采用阿普唑仑片治疗,观察组采用泻青丸合升降散治疗,2组均治疗2周。比较2组临床疗效,治疗前后采用汉密尔顿焦虑量表(HAMA)及匹兹堡睡眠质量指数量表(PSQI)评估患者的焦虑状况和睡眠质量。结果:观察组总有效率95.0%,对照组总有效率92.5%,2组比较,差异无统计学意义(P>0.05)。治疗后,2组躯体性焦虑评分、精神性焦虑评分及HAMA总分均较治疗前降低(P<0.05);观察组躯体性焦虑评分、精神性焦虑评分及HAMA总分均低于对照组(P<0.05)。治疗后,2组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍评分均较治疗前下降(P<0.05);对照组睡眠质量、入睡时间、睡眠时间、睡眠效率评分均低于观察组(P<0.05);2组睡眠障碍及日间功能障碍评分比较,差异无统计学意义(P>0.05)。观察组不良反应发生率5.0%,对照组不良反应发生率20.0%,2组比较,差异有统计学意义(P<0.05)。结论:泻青丸合升降散能有效改善肝郁化火型失眠症伴焦虑患者的症状。Objective：To observe the clinical effect of Xieqing pills combined with Shengjiang powder for insomnia and anxiety of syndrome of liver depression transforming into fire.Methods：Divided 80 cases of patients with insomnia and anxiety of syndrome of liver depression transforming into fire into the observation group and the control group randomly,40 cases in each group.The control group was given alprazolam tablets for treatment,while the observation group was given Xieqing pills combined with Shengjiang powder for treatment.The treatment lasted for two weeks in both groups.Compared the clinical effect in two groups and evaluated anxiety and quality of sleep by applying Hamilton anxiety scale（HAMA）and Pittsburgh sleep quality index（PSQI）.Results：The total effective rate was 95.0% in the observation group and was 92.5% in the control group,difference being insignificant（P 0.05）.After treatment,physical anxiety scores,psychological anxiety scores,and the total scores of HAMA in both groups were all decreased when compared with those before treatment（P 0.05）.The physical anxiety scores,psychological anxiety scores,and the total scores of HAMA in the observation group were lower than those in the control group（P 0.05）.After treatment,scores of the quality of sleep,the time of falling asleep,sleep time,sleep efficiency,sleep disorder,and daytime dysfunction in both groups were all decreased when compared with those before treatment（P 0.05）.The scores of quality of sleep,the time of falling asleep,sleep time,and sleep efficiency in the control group were all lower than those in the observation group（P 0.05）.There were no significant differences being found in the comparisons of scores of sleep disorder and daytime dysfunction in both groups（P 0.05）.The adverse reaction rate was 5.0% in the observation group and was 20.0% in the control group,difference being significant（P 0.05）.Conclusion：The therapy of Xieqing pills combined with Shengjiang powder can effectively improve sympto

关 键 词：失眠症 焦虑 肝郁化火证 泻青丸 升降散 汉密尔顿焦虑量表(HAMA) 匹兹堡睡眠质量指数量表(PSQI) 

分 类 号：R256.23[医药卫生—中医内科学]