阳和健脾汤治疗下肢动脉硬化闭塞症临床观察  

Clinical Observation of Yanghe Jianpi Tang for Arteriosclerosis Obliterans of Lower Extremities

作　　者：艾明瑞[1] 冉宪俊 王玉玲[1] 王艳青[1] 赵培[1] 张淑芳 高淑红[1] AI Mingrui;RAN Xianjun;WANG Yuling;WANG Yanqing;ZHAO Pei;ZHANG Shufang;GAO Shuhong

机构地区：[1]河北医科大学附属沧州中西医结合医院东院区疮疡脉管病科,河北沧州061000

出　　处：《新中医》2018年第4期99-101,共3页New Chinese Medicine

摘　　要：目的:观察阳和健脾汤对下肢动脉硬化闭塞症(ASO)的临床疗效。方法:将66例ASO患者随机分为2组各33例。对照组采用前列地尔等基础治疗,观察组在对照组治疗方案的基础上应用阳和健脾汤治疗。结果:总有效率对照组72.7%,观察组97.0%,2组比较,差异有统计学意义(P<0.05);治疗后,2组疼痛积分、冷感积分、踝肱比值(ABI)及皮温变化情况分别与治疗比较,差异均有统计学意义(P<0.05);2组间以上指标分别比较,差异均有统计学意义(P<0.05)。治疗后,2组甘油三酯、高密度脂蛋白胆固醇各项指标比较,差异均无统计学意义(P>0.05);2组间总胆固醇及低密度脂蛋白胆固醇指标比较,差异均有统计学意义(P<0.05)。结论:阳和健脾汤可改善患者症状,降低血液黏稠度,对肢端微循环、皮温及疼痛有较大改善,在临床治疗中值得使用。Objective：To observe the clinical effect of Yanghe Jianpi tang for arteriosclerosis obliterans of lower extremities（ASO）.Methods：Divided 66 cases of patients with ASO into two groups randomly,33 cases in each group.The control group received basic treatment of alprostadil,while the observation group additionally received Yanghe Jianpi tang based on the treatment of the control group.Results：The total effective rate was 72.7% in the control group and was 97.0%in the observation group,the difference being significant（P 0.05）.After treatment,compared changes of scores of pain,sense of coldness and ABI,as well as skin temperature before and after treatment between the two groups,differences being significant（P 0.05）.The respective comparisons of above indexes between the two groups showed significance in differences（P 0.05）.After treatment,no significant difference was found in the comparisons of indexes of triglyceride and high density lipoprotein cholesterol between the two groups（P 0.05）.The comparisons of total cholesterol and low density lipoprotein cholesterol between the two groups showed significance in differences（P 0.05）.Conclusion：Yanghe Jianpi tang can effectively improve symptoms of patients,reduce blood viscosity and significantly improve acral microcirculation,sense of coldness and pain,which is worthy of clinical application.

关 键 词：下肢动脉硬化闭塞症(ASO) 阳和健脾汤 前列地尔 疼痛积分 冷感积分 皮温变化情况 总胆固醇 踝肱比值(ABI) 

分 类 号：R543.5[医药卫生—心血管疾病]