呼吸机相关性肺念珠菌感染的危险因素分析  

RISK FACTORS FOR VENTILATOR-ASSOCIATED PULMONARY CANDIDA ALBICANS INFECTION

作　　者：石新艳[1] 刘颖[2] 芦海英[2] 王升英[2] 王虹[3] 韩伟[4] SHI Xinyan;LIU Ying;LU Haiying;WANG Shengying;WANG Hong;HAN Wei(DepartmentofGeneralSurgery, TheAffiliatedHospitalof Qingdao University, Qingdao 266003, Chin)

机构地区：[1]青岛大学附属医院普通外科,山东青岛266003 [2]青岛市市立医院骨关节与运动医学科 [3]青岛市市立医院医院感染管理科 [4]青岛市市立医院呼吸科

出　　处：《青岛大学医学院学报》2017年第5期508-510,共3页Acta Academiae Medicinae Qingdao Universitatis

基　　金：国家自然科学基金资助项目(81400024)

摘　　要：目的了解某院呼吸机相关性肺念珠菌感染情况,探讨其危险因素,为制定有效的预防控制措施提供依据。方法对2013—2016年某院呼吸机相关性肺念珠菌感染的病例进行回顾性调查分析。结果 667例使用呼吸机病人中发生呼吸机相关性肺念珠菌感染41例,感染率为6.06%。年龄大、住院时间长、呼吸系统疾病、低蛋白血症、长时间应用免疫抑制剂与不合理使用抗菌药物是呼吸机相关性肺念珠菌感染的危险因素。结论加强医院感染管理,减少住院时间与合理用药是降低呼吸机相关性肺念珠菌感染的有效方法。Objective To investigate the status of ventilator-associated pulmonary Candida albicans infection and related risk factors,and to provide a basis for developing effective preventive and control measures.Methods A retrospective analysis was performed for the patients who experienced ventilator-associated pulmonary Candida albicans infection in a hospital from 2013 to 2016.Results Of all 667 patients who used a ventilator,41 experienced ventilator-associated pulmonary Candida albicans infection,resulting in an infection rate of 6.06%.Old age,long length of hospital stay,respiratory disease,hypoproteinemia,longterm application of immunosuppressant,and unreasonable use of antibacterial agents were risk factors for ventilator-associated pulmonary Candida albicans infection.Conclusion Strengthening nosocomial infection management,shortening the length of hospital stay,and promoting rational drug use are effective methods for reducing ventilator-associated pulmonary Candida albicans infection.

关 键 词：念珠菌属 肺炎 呼吸机相关性 危险因素 

分 类 号：R563.1[医药卫生—呼吸系统] R379.4[医药卫生—内科学]