二叶式主动脉瓣伴升主动脉扩张患者血流状况的计算流体动力学数值模拟方法分析  

Numerical simulation of blood flow status in bicuspid aortic valve with ascending aorta dilatation using computational fluid dynamics

作　　者：乔志钰[1] 郑铁[1] 朱帅[1] 齐瑞东[1] 程力剑[1] 葛翼鹏[1] 陈雷[1] 里程楠[1] 胡海瓯[1] 夏瑀[1] 朱俊明[1] 张楠[2] Qiao Zhiyu;Zheng Tie;Zhu Shuai;Qi Ruidong;Cheag Lifian;Ge Yipeng;Chen Lei;Li Chengnan;Hu Haiou;Xia Yu;Zhu Junming;Zhang Nan(Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Belting Institute of Heart Lung and Blood Vessel Diseases, Beijing Aortic Disease Center, Beijing 100029, China;Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China)

机构地区：[1]首都医科大学附属北京安贞医院心血管外科北京市心肺血管疾病研究所北京市大血管疾病诊疗研究中心,100029 [2]首都医科大学附属北京安贞医院放射影像科,100029

出　　处：《中国医药》2018年第4期530-533,共4页China Medicine

基　　金：国家科技支撑计划(2015BAI12B03);国家卫生和计划生育委员会公益性行业科研专项(201402009)~~

摘　　要：目的应用计算流体动力学(CFD)数值模拟方法分析二叶式主动脉瓣(BAV)伴升主动脉扩张患者的血流状况。方法用磁共振成像仪器扫描的1例BAV伴升主动脉扩张患者的影像学资料,利用CFD数值建模,分析血流动力学状况。结果扩张部位有流速较高区域并往外侧偏移,扩张部位有流速较高区域壁面压强均较高,升主动脉近端切应力较高,集中于升主动脉窦管交界部及升主动脉窦管交界以上2 cm处。结论通过CFD数值模拟方法可以对BAV患者进行血流动力学研究分析。Objective To analyze the blood flow status in bicuspid aortic valve （BAV） with ascending aorta dilatation by computational fluid dynamics （CFD） numerical simulation method. Methods Magnetic resonance imaging data of one case of BAV with ascending aortic dilatation were analyzed by CFD numerical modeling. Results The dilatation region showed a high flow velocity region; the high velocity region showed a high wall pressure ; the proximal end of ascending aorta showed a high shearing stress at the junction of ascending aortic sinus canal and 2 em above the junction of ascending aortic sinus canal. Conclusion CFD numerical simulation method can be used to study the hemodynamic factors of BAV patients.

关 键 词：二叶式主动脉瓣 升主动脉扩张 计算流体动力学 血流动力学 

分 类 号：R543.1[医药卫生—心血管疾病]