探究地塞米松与卡前列素氨丁三醇对高危妊娠产妇产后的止血效果  

The Effect of Dexamethasone and Carboprost Tromethamine on Postpartum Hemostasis in High-risk Pregnant Women

作　　者：代满荣 李军[2] DAI Manrong;LI Jun(Department of Obstetrics and Gynecology, Xiantao City First People＇s Hospital Afliated to Yangtze University, Xiantao Hubei 433000, China;Department of Cardiovascular Medicine)

机构地区：[1]长江大学附属仙桃市第一人民医院妇产科,湖北仙桃433000 [2]长江大学附属仙桃市第一人民医院心血管内科,湖北仙桃433000

出　　处：《中国继续医学教育》2018年第14期137-139,共3页China Continuing Medical Education

摘　　要：目的探究地塞米松与卡前列素氨丁三醇联用对高危妊娠产妇产后出血的疗效。方法搜集100例高危妊娠产妇产后出血患者作为研究对象,按照治疗方式不同均等分为对照组(50例,行卡前列素氨丁三醇治疗)和实验组(50例,地塞米松+卡前列素氨丁三醇治疗)。结果实验组、对照组的治疗总有效率分别为92.00%、82.00%,P>0.05。实验组不良反应发生率为20.00%,明显低于对照组的44.00%,P<0.05。实验组患者分娩后12 h内及24 h平均失血量分别为(285.21±50.21)ml、(327.47±49.11)ml;明显低于对照组患者的(342.43±48.22)ml、(542.66±57.25)ml,均P<0.05。结论地塞米松与卡前列素氨丁三醇联用对高危妊娠产妇产后出血的治疗,达到快速止血的目的。Objective To investigate the curative efect of dexamethasone and carboprost trometamol on postpartum hemorrhage in high risk pregnancy. Methods 100 cases of maternal postpartum hemorrhage in high risk pregnancy were collected and divided into control group （50 cases, carboprost trometamol treatment） and experimental group （50 cases, dexamethasone ＋ carboprost trometamol treatment）. Results The total efective rates of the experimental group and the control group were 92.00% and 82.00%, respectively, P 〉 0.05. The incidence of adverse reactions in the experimental group was 20.00%, which was significantly lower than that in the control group of 44.00%, P 〈 0.05. The average blood loss within 12 h and 24 h after the delivery in the experimental group were （285.21 ± 50.21） ml and （327.47 ± 49.11） ml were signifcantly lower than the control group of （342.43 ± 48.22） ml and （542.66 ± 57.25） ml, respectively, all P 〈 0.05. Conclusion The combination of dexamethasone and carboprost tromethamine in the treatment of postpartum hemorrhage in high-risk pregnancies achieves the purpose of rapid hemostasis and can be promoted.

关 键 词：高危妊娠产妇 产后出血 地塞米松 卡前列素氨丁三醇 疗效 

分 类 号：R714[医药卫生—妇产科学]