微波合成5-(3-羟基-1,3-二苯基烯丙基)麦氏酸  

Microeave synthesis 5-( 3-hydroxy-1,3-aiiyldiphenyl) medrum's acid

作　　者：李文林[1] 王东林 周立王 赵宙兴[1] LI Wenlin, WANG Donglin, ZHOU Liwang, ZHAO Zhouxing(School of Chemical Engineering , Qinghai University, Xining 810016, Chin)

机构地区：[1]青海大学化工学院,青海西宁810016

出　　处：《青海大学学报（自然科学版）》2018年第2期89-92,共4页Journal of Qinghai University(Natural Science)

基　　金：青海大学2016年专业核心课程建设项目(2016ZYHXKC09)

摘　　要：以查尔酮和麦氏酸为原料,经微波辐照合成了5-(3-羟基-1,3-二苯基烯丙基)麦氏酸,合成的最佳条件为DMF做反应介质,n(麦氏酸)∶n(查尔酮)=1.2∶1,微波中火辐照30 min,产物收率为87.6%。目标化合物结构经红外光谱(FT-IR)、核磁共振氢谱(~1H NMR)和核磁共振碳谱(^(13)C NMR)表征确证。5-（ 3-hydroxy-1,3-allyl diphenyl） Medrum’ s acid was synthesized with chalcone ketones and Medrum’s acid. The optimum reaction conditions were obtained： ratio of chalcone ketones to Medrum’s acid 1. 2∶ 1,in DMF dissolved intermittent microwave for 30 minutes. The yield under this optimum reaction conditions was up to 87. 6%,The structure of the target product was confirmed by elementary analysis,FT-IR,1 H NMR and 13 C NMR spectroscopy.

关 键 词：微波法 麦氏酸 查尔酮 5-(3-羟基-1 3-二苯基烯丙基)麦氏酸 

分 类 号：O623.55[理学—有机化学]