阴道残端液基细胞学筛查在因良性病变全子宫切除术后随访中的临床意义  

Clinical significance of vaginal cytology tests in women withhysterectomoy for benign diseases

作　　者：沈艳[1] 李慧卉 杨锐[1] 夏静 SHEN Yan;LI Huihui;YANG Rui;XIA Jing.(Wuhan Union Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430022, Chin)

机构地区：[1]华中科技大学同济医学院附属协和医院体检中心,武汉430022

出　　处：《中国生育健康杂志》2018年第3期205-207,218,共4页Chinese Journal of Reproductive Health

摘　　要：目的探讨因良性病变切除全子宫后的阴道残端液基细胞学检测(LCT)的临床意义。方法回顾性分析武汉协和医院体检中心2013年1月—2016年8月进行过妇科体检的24 239位女性的细胞学筛查结果,比较因良性病变切除全子宫者(1 118例)和未行此术者(23 121例)中细胞学筛查结果异常的发生率,并评估异常的发生与年龄的关系。结果在因良性病变切除全子宫者中,LCT结果为非典型鳞状细胞(ASCs)者约6.5%,低度鳞状上皮内病变(LSIL)者约0.5%,而在未切除全子宫者中,LCT结果为ASCs及LSIL者分别约14.7%、1.9%,两组中ASCs及LSIL的风险比(95%CI)分别为0.4(0.3~0.6)、0.2(0.1~0.6),子宫切除组细胞学结果的异常与年龄的差异无统计学意义。结论因良性病变切除全子宫后的阴道残端LCT结果中,ASCs及LSIL的患病率明显低于未行此术者。术后进行常规LCT筛查临床意义不大。Objective To discuss the clinical significance of vaginal liguid-based cytology test （LCT） after hysterectomy for benign diseases. Methods A retrospective study was made of 24 239 womens＇ cytology results, who were tested at Wuhan Union Hospital from January 2013 to August 2016. Comparing the prevalence of abnormal results in women who had undergone a hysterectomy for benign diseases（ n = 1 118） to that of women had had no hysterectomy （n =23 121）,and assessing the relationship between the prevalence and age. Results The prevalence of atypical squamous cells （ ASCs ）, low-grade squamous intraepithelial lesion （ LSIL ） was approximately 6. 5% and 0. 5%, respectively,in women who had undergone hysterectomy , and about 14. 7% , 1.9% in women who had not undergone hysterectomy. The prevalence ratio（PR） with 95% confidenee intervals（95% CI） for ASCs, LSIL was 0. 4 （0. 34）. 6）, 0. 2（0. 14）. 6）, respectively, in women with a hysterectomy versus those without. The prevalence rates in women with hysterectomy had no statistically significant variation with age. Conclusion The prevalence rates of abnormal cytology- tests in women who had undergone hysterectomy were obviously under that of women had had no hysterectomy. There was no clinical significance about the vaginal cytology- tests after hysterectomy for benign diseases.

关 键 词：全子宫切除术 阴道残端细胞学检测 非典型鳞状细胞 低度鳞状上皮内病变 

分 类 号：R713.42[医药卫生—妇产科学]