胎盘绒毛膜血管瘤病临床病理分析  

Clinicopathological Analysis of Placental Chorioangiomatosis

作　　者：廖欣[1] 邹娟[1] 孙亮[1] 杨帆[1] Liao Xin;Zou Juan;Sun Liang;et al.(Key Laboratory of Ministry of Education for Birth Defects and Related Diseases of Women and Children, Department of Pathology, West China Second Hospital of Sichuan University, Chengdu , Sichuan 610041, China)

机构地区：[1]四川大学华西第二医院病理科出生缺陷与相关妇儿疾病教育部重点实验室,四川成都610041

出　　处：《四川医学》2018年第3期312-315,共4页Sichuan Medical Journal

摘　　要：目的探讨胎盘绒毛膜血管瘤病(Chorangiomatosis,CM)的临床病理特征、相关妊娠期及围生儿合并症、诊断及鉴别诊断。方法对9例胎盘CM的临床及病理资料进行回顾性研究,并对围生儿情况进行1年随访。结果 9例胎盘CM中,2例为弥漫性CM,7例为局限性CM;9例CM均伴有妊娠期合并症,包括先兆子痫、胎膜早破、胎盘早剥及妊娠期糖尿病等;9例新生儿产后1年均存活,包括双胎2例,早产儿5例,宫内发育迟缓(Intrauterine Growth Retardation,IUGR)2例及肥厚性心肌病1例。结论胎盘CM是一类较为罕见的胎盘绒毛血管疾病,目前主要依赖产后胎盘病理诊断,尤其需要与胎盘绒毛膜血管瘤(Chorangioma,CA)和胎盘绒毛膜血管病(Chorangiosis,CH)进行鉴别;胎盘CM与多种妊娠期及新生儿并发症相关,需引起重视。Objective To investigate the clinicopathological features,associated complications of pregnancy and perinatal infants,diagnosis and differential diagnosis of placental chorioangiomatosis（ CM）.Methods The clinical and pathological data of 9 cases of placental CM were retrospectively studied,and the perinatal condition was followed up for 1 year. Results In 9 cases of placental CM,2 cases were diffuse CM and 7 cases were localized CM; 9 cases of CM were associated with complications of pregnancy,including preeclampsia,premature rupture of membranes,placental abruption and gestational diabetes mellitus; 9 cases of newborns survived 1 year after postpartum,including 2 cases of twins,5 cases of premature infants,and 2 cases of Intrauterine Growth Retardation（ IUGR） and 1 case of hypertrophic cardiomyopathy.Conclusion Placental CM is a rare type of placental chorionic vascular disease.At present,it mainly relies on postpartum placental pathological diagnosis,especially differentiated from placental Chorangioma（ CA） and placental Chorangiosis（ CH）; Placental CM is associated with multiple pregnancy and neonatal complications,which needs attention.

关 键 词：绒毛膜血管瘤病 胎盘 绒毛 绒毛膜血管瘤 绒毛膜血管病 

分 类 号：R714.56[医药卫生—妇产科学]