MRI矢状位T2图在腰椎分级中的量化分析  

Quantitative Analysis of Lumbar Disc Classification in MRI Sagittal T2 Mapping

作　　者：蔡绍磊 邓和平 陈锦秀 吴梅[2] 徐宏刚[2] 王海林[2] 阴骏 Cai Shaolei;Deng tteping;Chen Jinxtu;et al(Department of Radiology, Guangzhou First People＇s Hospital, G uangzhou, Guangdong 51 0180, China)

机构地区：[1]四川省肿瘤医院·研究所放疗科、四川省癌症防治防治中心、电子科技大学医学院,四川成都610041 [2]广州市第一人民医院放射科,广东广州510180

出　　处：《四川医学》2018年第3期353-357,共5页Sichuan Medical Journal

摘　　要：目的利用MRI矢状位T2图(矢状位多回波SE序列T2 mapp Ing),探讨椎间盘髓核和纤维环T2值改变在椎间盘退变中的意义,并以此进行椎间盘分级的可行性和有效性。方法随机选取30位健康志愿者(18男,12女;年龄21~49岁;平均年龄34.1岁),均利用常规FSE序列和多回波SE序列对L3/4、L4/5、L5/S1共90个椎间盘进行MRI矢状位扫描。通过图像后处理进行T2图成像(T2 mapp Ing)并对各椎间盘进行分级;测量椎间盘髓核和纤维环T2值,针对T2值与年龄、椎间盘级别、椎间盘位置之间的关系,进行统计学分析。结果 MRI矢状位T2图分级法中,椎间盘级别随着椎间盘位置的降低而增高,随年龄的增加而增高。髓核T2值随着年龄增大而减低,差异有统计学意义(P<0.05);各级别椎间盘髓核T2均值间差异有统计学意义(P<0.05)。结论 MRI矢状位T2图提供了一个建立在T2值上的椎间盘分级方法,通过对T2图的评估及椎间盘髓核和纤维环T2值的测量,有助于监测椎间盘早期退行性改变以及和相关因素的关系。Objective To discuss significance of T2 value changes of nucleus pulposus and annulus fibrosus in intervertebral disc degeneration,and to discuss the feasibility and effectivity of intervertebral disc classification according to it,through MRI sagittal T2 mapping（ e.g.sagittal multi-echo SE sequence T2 mapping）. Methods 30 healthy volunteers（ including 18 males and12 females,aged 21 to 49,with an average age of 34. 1） were randomly selected and their intervertebral discs of L3/L4,L4/L5 and L5/S1,with a sum-up of 90 discs,were scanned by sagittal MRI using routine FSE sequence as well as multi-echo SE sequence.T2 mapping was performed by image post-processing and each intervertebral disc was classified.T2 values of nucleus pulposus and annulus fibrosus were measured and statistical analysis were performed to study the relationship between T2 values and ages,disc grades or disc locations.Results In classification through MRI sagittal T2 mapping,the disc grade increased along with the decrease of disc location or the increase of age. T2 value of nucleus pulposus decreased along with the increase of age（ P〈0. 05）.There was a statistically significant difference in T2 mean values of nucleus pulposus of different grades（ P〈0. 05）. Conclusion MRI sagittal T2 mapping provides us with a classification of intervertebral disc based on T2 values.Through evaluation of T2 mapping and measurement of T2 values of nucleus pulposus and annulus fibrosus,early stage degeneration of intervertebral disc can be monitored and the its relationship with relevant factors can be studied.

关 键 词：腰椎 椎间盘 退行性变 磁共振成像 T2图 

分 类 号：R681.53[医药卫生—骨科学] R445.2[医药卫生—外科学]