高剂量氟康唑治疗近平滑念珠菌感染的药学监护1例分析  

Pharmaceutical care for a patient with parapsilosis Candidaemia treated with high dose Fluconazole

作　　者：钟玲[1] 娄艳[2] 黎奔[1] ZHONG Ling1, LOU Yan2, LI Ben1(1.Department of Pharmacy, the Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guang- dong Province, Guangzhou 510120, China; 2.Department of Pharmacy, Narffang Hospital of Southern Medical University, Guangdong Province, Guangzhou 510515, Chin)

机构地区：[1]广州中医药大学第二临床医学院药学部,广东广州510120 [2]南方医科大学南方医院药学部,广东广州510515

出　　处：《中国医药导报》2018年第10期127-130,共4页China Medical Herald

基　　金：广东省中医院中医药科学技术研究专项资助(YN2016YX03)

摘　　要：氟康唑是一种三唑类抗真菌药,广泛应用于念珠菌及隐球菌感染的治疗。随着念珠菌耐药问题的日益突出,抗真菌药物的选择及使用剂量的把握也成为临床用药的难点。本文从疾病诊断、治疗及高剂量氟康唑使用安全性等角度,结合药学监护,对1例使用高剂量氟康唑治疗近平滑念珠菌血症的病例进行分析,对用药安全性及合理性进行评估、干预,为临床合理应用氟康唑治疗近平滑念珠菌血症提供参考。Fluconazole, a three azole antifungal agent, is widely used in the treatment of Candida and Cryptococcal infections. However, with the increasingly prominent problem of Candida resistance, the choice of antifungal drugs and the use of dose has become a difficult point in clinical medication. This paper makes analysis for a case with parapsilosis Candidaemia treated with high dose Fluconazole, from the angle of disease diagnosis, treatment and the safety of high dose Fluconazole, combined with pharmaceutical car, and evaluates and intervenes the safety and rationality of drug use. The article provides reference for clinical rationly application of Fluconazole in the treatment of parapsilosis Candidaemia.

关 键 词：高剂量氟康唑 安全性 近平滑念珠菌血症 药学监护 临床药师 

分 类 号：R97[医药卫生—药品]