自体富血小板血浆与全血局部注射治疗网球肘的疗效比较  

Comparison of autologous platelet-rich plasma and whole blood local injection in the treatment of tennis elbow

作　　者：王艳杰[1] 吴骁[1] 孙育良 WANG Yan-jie;WU Xiao;SUN Yu-liang(Sichuan Provincial Orthopedic Hospital, Chengdu , Sichuan 610041, China)

机构地区：[1]四川省骨科医院,四川成都610041

出　　处：《中国临床研究》2018年第4期527-530,共4页Chinese Journal of Clinical Research

基　　金：四川省科技厅重点项目(2016JY0052)

摘　　要：目的对比自体富血小板血浆(PRP)与自体全血(AWB)局部注射治疗网球肘的治疗方法及疗效。方法2015年1月至2016年12月门诊收治网球肘患者50例,随机分成PRP组和AWB组,每组25例。PRP组男10例,女15例;年龄(47.34±7.80)岁;病程(5.35±1.41)个月,采用2 ml自体PRP进行痛点局部注射。AWB组男8例,女17例;年龄(48.81±9.27)岁;病程(5.88±1.37)个月,采用2 ml AWB进行痛点局部注射。两组均在门诊行一次治疗。治疗后,用弹力绷带制动3 d,并嘱患者少做伸腕、拧手帕等动作。治疗前及治疗后6周分别对患者进行视觉模拟评分法(VAS)、Mayo肘关节评分,并对比两种治疗方法的疗效。结果全部患者获得随访6周,随访中未发现相关并发症。治疗6周后,PRP组患者VAS评分为(2.41±0.94)分,AWB组为(3.50±0.99)分,两组差异有统计学意义(P<0.01);PRP组在Mayo肘关节评分疼痛、活动度、稳定性、日常能力四个方面的得分及总分分别为(42.69±5.52)分、(19.42±1.63)分、(9.62±1.96)分、(23.27±2.43)分和(95.00±8.12)分,均优于AWB组的(40.38±7.06)分、(18.65±2.26)分、(8.85±3.26)分、(22.31±3.23)分和(86.73±6.77)分,差异有统计学意义(P均<0.01)。结论自体富血小板血浆局部注射治疗网球肘疗效优于自体全血治疗。Objective To compare the clinical effect of autologous platelet-rich plasma（PRP） and whole blood（AWB）local injection in the treatment of tennis elbow. Methods Fifty tennis elbow patients from January 2015 to December 2016 were selected and divided into PRP group and AWB group randomly（25 patients each）. The PRP group patients,including10 males and 15 females,were（47. 34 ± 7. 80） years old,and the course of disease was（5. 35 ± 1. 41） months,and received pain point injection with 2 ml autologous PRP. The AWB group patients,including 8 males and 17 females,were（48. 81 ± 9. 27） years old,and the course of disease was（5. 88 ± 1. 37） months,and received pain point injection with2 ml AWB. Both groups were treated at outpatient department. After treatment,all the patients＇ elbow was fixed by elastic bandage for 3 days and were told do less wrist action and twist handkerchief. The Visual Analogue Scale（VAS） and Mayo elbow performance score（MEPS） were evaluated before and 6 weeks after the treatment,and the difference of the curative effect between the two methods was compared. Results All patients were followed up,and no related complications were found during the follow-up. The VAS in PRP group was lower than that in AWB group（2. 41 ± 0. 94 vs 3. 50 ± 0. 99,P 0. 01） at 6 weeks after the treatment. The pain,motion,stability,daily function score and total score of MEPS in PRP group were significant higher than those in AWB group（42. 69 ± 5. 52 vs 40. 38 ± 7. 06,19. 42 ± 1. 63 vs 18. 65 ± 2. 26,9. 62 ±1. 96 vs 8. 85 ± 3. 26,23. 27 ± 2. 43 vs 22. 31 ± 3. 23,95. 00 ± 8. 12 vs 86. 73 ± 6. 77,all P 0. 01）. Conclusion Clinical effect of autologous PRP local injection is better than AWB in the treatment of tennis elbow.

关 键 词：网球肘 富血小板血浆 自体全血 局部注射 

分 类 号：R686[医药卫生—骨科学]