阿莫西林与阿莫西林-克拉维酸钾不良反应的对比研究  

Comparative Study on Adverse Reactions of Amoxicillin and Amoxicillinande Clavulanate Potassium

作　　者：胡俊华[1] 孟秋媛 胡艳秋[3] HU Jun-hua;MENG Qiu-yuan;HU Yan-qiu(Jiamusi Municipal Center for Disease Control and Prevention, Jiamusi, Heilongjiang, 154007, China)

机构地区：[1]佳木斯市疾病预防控制中心,黑龙江佳木斯154007 [2]佳木斯大学附属第一医院,黑龙江佳木斯154002 [3]佳木斯大学药学院,黑龙江佳木斯154007

出　　处：《中国初级卫生保健》2018年第4期74-75,共2页Chinese Primary Health Care

摘　　要：目的探讨阿莫西林和阿莫西林-克拉维酸钾的不良反应情况。方法选取佳木斯大学附属第一医院180例支气管感染患者进行分析研究,分为对照组和观察组,每组各90例患者,对照组患者给予阿莫西林治疗,观察组给予阿莫西林-克拉维酸钾治疗,比较两组患者的不良反应情况。结果观察组患者的不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。两组的治疗效果对比,观察组优于对照组,差异具有统计学意义(P<0.05)。结论感染性疾病患者接受阿莫西林-克拉维酸钾治疗的安全性高于阿莫西林,临床应用安全性较高。OBJECTIVE To investigate the adverse reactions of amoxicillin and amoxicillin and clavulanate potassiun. METHODS In the First Affiliated Hospital of Jiamusi University, 180 cases of patients with bronchial infection diseases were divided into control group an observation group, 90 cases in each group. Patients in the control group received amoxicillin for treatment, the observation group received amoxicillin and clavulanic potassium, compared two groups of patients with adverse reactions. RESULTS The incidence of adverse reactions in the observation group was lower than the control group, the difference was significant（P〈0.05）. The therapeutic effects of the two groups were compared, the observation group was better than the control group, and the results were statistically significant（P〈0.05）. CONCLUSION It was safe to use amoxicillin and clavulanate potassium for patients with infectious diseases,and the clinical application safety was high.

关 键 词：阿莫西林 阿莫西林-克拉维酸钾 不良反应 

分 类 号：R978.1[医药卫生—药品]