隐球菌性脑膜炎诊治专家共识  

Expert consensus on the diagnosis and treatment of cryptococcal meningitis

作　　者：刘正印[1] 王贵强[2] 朱利平[3] 吕晓菊[4] 章强强[5] 俞云松[6] 周志慧[6] 刘焱斌[4] 蔡卫平[7] 李若瑜[8] 张文宏[3] 张福杰[9] 吴昊 徐英春[11] 卢洪洲[12] 李太生[1] Liu Zhengyin;WangGuiqiang;Zhu Liping;Lyu Xiaoju;Zhang Qiangqiang;Yu Yunsong;Zhou Zhihui;Liu Yanbin;Cai Weiping;Li Ruoyu;Zhang Wenhong;Zhang Fujie;Wu Hao;Xu Yingchun;Lu Hongzhou;Li Taisheng(Department of Infectious Diseases, Peking Union Medical College;Society of Infectious Diseases, Chinese Medical Association Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院感染内科,100730 [2]北京大学第一医院感染科 [3]复旦大学华山医院感染科 [4]四川大学华西医院感染科 [5]复旦大学华山医院皮肤科 [6]浙江大学附属邵逸夫医院感染科 [7]广州市第八人民医院感染病科 [8]北京大学第一医院皮肤科 [9]首都医科大学附属北京地坛医院感染中心 [10]首都医科大学附属北京佑安医院感染中心 [11]中国医学科学院北京协和医学院北京协和医院检验科,100730 [12]上海市公共卫生中心

出　　处：《中华内科杂志》2018年第5期317-323,共7页Chinese Journal of Internal Medicine

摘　　要：引言2000年，美国感染病学会（Infectious Diseases Society of America，IDSA）首次发表了“隐球菌病治疗的实践指南”，2010年更新为“隐球菌病治疗临床实践指南，美国感染病学会2010更新”，该指南经过多年临床应用，确实发挥了规范隐球菌感染治疗的作用；但是在我国临床实施过程中，的确发现有很多不适用于中国的内容。Cryptococcal meningitis is a common and refractory central nervous system infection, with high rates of mortality and disability. The experts of the Society of Infectious Diseases of Chinese Medical Association have reached this consensus after a thorough discussion. Based on the current situation of cryptococcal meningitis in China, the management of cryptococcal meningitis includes 6 aspects： introduction, microorganism identification, clinical manifestations and diagnosis, principles of antifungal therapy, treatment of refractory and recurrent meningitis, treatment of intracranial hypertension. There is not a separate consensus on human immunodeficiency virus （HIV） infection in patients with cryptococcal meningitis. This article focuses on different antifungal regimens and reducing intracranial pressure by reference to Infectious Disease Society of America （IDSA） guidelines. The importance of early diagnosis, combined long-term antifun^al therapy, control of intracranial hvDertension are emphasized.

关 键 词：隐球菌性脑膜炎 临床实践指南 Diseases 专家 诊治 隐球菌病 隐球菌感染 临床应用 

分 类 号：R519.4[医药卫生—内科学]