2013—2016年新疆流感病原学监测结果  

Etiologic surveillance results of influenza in Xinjiang from 2013-2016

作　　者：张璇[1] 毋跃文[1] 郜振国[1] 赵俊[1] 刘红斌[1] 马合木提[1] ZHANG Xuan;WU Yue-wen;GAO Zhen-guo;ZHAO Jun;LIU Hong-bin;MAHEMUTI(Department of lnfections Disease Control and Preventing,Xinjiang Center for Disease Control and Prevention,Xinjiang Urumqi 830002, Chin)

机构地区：[1]新疆维吾尔自治区疾病预防控制中心传染病防治科,新疆乌鲁木齐830002

出　　处：《职业与健康》2018年第6期796-799,共4页Occupation and Health

摘　　要：目的收集新疆2013—2016年流行性感冒流行特征,为流感防控工作提供科学依据。方法了解新疆哨点医院流感样病例(ILI)就诊资料,对采集的部分患者样本使用实时荧光PCR进行流感病毒亚型鉴定,阳性标本用MDCK细胞进行病毒分离。结果 2013年10月—2016年9月新疆共计门诊病例9 222 413例,其中流感样病例(ILI)444 470例,占就诊人数百分比(ILI%)为4.8%;病例主要集中在<5岁儿童。检测流感样病例咽拭子标本4 882份,检出流感病毒阳性1 679株,阳性率为33.63%,其中新甲型H1N1 422株,H3型646株,BV型330株,BY型244株,聚集性疫情中病毒型别与当年流行的病毒型别基本一致。新疆流感发病主要集中在每年12月—次年3月,2013年10月—2014年9月新甲H1N1为绝对优势株,2014年10月—2015年9月季节性流感H3为绝对优势株,2015年10月—2016年9月则是以2到3种流感病毒混合交替出现为主。结论新疆流感主要发生在冬春季,累及青少年人群为主,应加强青少年的流感防控工作。[Objective] To understand the epidemic characteristics of influenza in Xinjiang from 2013 to 2016,provide the scientific basis for the control and prevention of influenza.[Methods]The influenza like illness（ILI） cases in sentinel hospitals of Xinjiang were investigated. The influenza virus subtype identification was performed by real-time PCR method and virus isolation of positive specimens was conducted with MDCK cells. [Results]From October 2013 to September 2016,there were totally 9 222 413 outpatients in Xinjiang,including 444 470 ILI cases,with the percentage of patients（ILI%） of 4.8%. And they were mainly concentrated in the children under 5 years old. 1 679 strains of influenza virus were isolated from 4 882 swab specimens with an isolation rate of 30.39%,including 422 strains of influenza A H1 N1,646 strains of H3,330 strains of BV and244 strains of BY. The virus type of aggregation epidemic was same as the dominant virus type of that year. The peak season of influenza in Xinjiang appeared December to the next March. The novel influenza A（H1 N1） was the absolute dominant type from October 2013 to September 2014,and seasonal H3 was the absolute dominant type from October 2014 to September 2015,while2-3 kinds of influenza viruses were dominant alternately from October 2015 to September 2016.[Conclusion]In Xinjiang,the influenza mainly occurs in winter and spring,and adolescent is the high-risk population. It is necessary to strengthen the prevention and control of influenza on teenagers.

关 键 词：流感 流行状况 监测 

分 类 号：R181.3[医药卫生—流行病学]