右美托咪定用于无痛胃肠镜麻醉的临床应用分析  

Clinical Application Analysis of Dexmedetomidine in Painless Gastroenteroscopy Anesthesia

作　　者：于振峰[1] 张惠珍[1] YU Zhen-feng;ZHANG Hui-zhen(Department of Anesthesiology, Baotou City Mongolian and Traditional Chinese Medicine Hospital, Baotou, Inner Mongolia 014040)

机构地区：[1]包头市蒙医中医医院麻醉科,内蒙古包头014040

出　　处：《智慧健康》2018年第5期104-105,共2页Smart Healthcare

摘　　要：目的探讨分析右美托咪定(恒瑞-艾贝宁)用于无痛胃肠镜麻醉的临床效果。方法采用随机分组的方式将2016年8月至2017年8月间收治的80例无痛胃肠镜诊疗患者分为两组,对照组麻醉药物为芬太尼,实验组麻醉药物为右美托咪定,评估两组麻醉效果。结果两组MAP、HR、SpO2三项指标在T1时点的差异无统计学意义(P>0.05);实验组T2时点的MAP、HR、SpO2三项指标优于对照组,独立样本t检验提示两组数据差异显著(P<0.05)。与对照组相比,实验组VAS评分更低,可唤醒时间更短,独立样本t检验提示两组数据差异具有统计显著性(P<0.05);两组丙泊酚用量无显著差异(P>0.05);对照组中恶心呕吐4例,体动3例,辅助呼吸7例,实验组中恶心呕吐0例,体动1例,辅助呼吸0例,卡方检验提示两组数据差异具有统计显著性(P<0.05)。结论右美托咪定是临床开展无痛胃肠镜诊疗的常用麻醉药物,其麻醉效果确切,不良反应少,更有利于无痛胃肠镜诊疗工作顺利完成。Objective To investigate and analyze clinical effect of dexmedetomidine（Hengrui-Abotning） for painless gastroenteroscopy anesthesia. Methods Divide 80 cases painless gastroenteroscopy patients from August 2016 to August 2017 into two groups by random grouping method. Control group was treated with fentanyl anesthesia, and experimental group with dexmedetomidine anesthesia. Evaluate anesthetic effect of two groups. Results Indexes of MAP, HR and SpO2 of two groups at T1 time point showed no significant difference,（P〉0.05）. MAP, HR and SpO2 of experimental group at T2 time point was superior to control group. Independent sample t test suggested data difference showed significance between two groups,（P〈0.05）. VAS scores of experimental group were lower and control group, wake-up time was shorter. Independent sample t test suggested data difference showed statistical significance between two groups,（P〈0.05）, propofol dosage showed no significant difference between two groups,（P〉0.05）. 4 cases of nausea and vomiting occurred in control group, 3 cases of body movement, 7 cases of auxiliary respiration, 0 case of nausea and vomiting occurred in experimental group, 1 case of body movement, 0 case of auxiliary respiration. Chi square test suggested data difference showed statistical significance between two groups,（P〈0.05）. Conclusion Dexmedetomidin is common anesthetic for diagnosis and treatment of painless gastroenteroscopy, with accurate anesthetic effect and less adverse reaction, which is conducive to smooth fulfilment of painless gastroenteroscopy.

关 键 词：无痛胃肠镜 右美托咪定 芬太尼 临床 

分 类 号：R614[医药卫生—麻醉学]