经皮微波消融治疗复发性小肝细胞肝癌的近期疗效研究  

Study of Short-term Efficacy of Percutaneous Microwave Ablation in the Treatment of Recurrent Small Hepatocellular Carcinoma

作　　者：张浩[1] 俞小炯[1] Zhang Hao;Y-u Xiaojiong.(Sichuan Provincial Academy of Medical Sciences · Sichuan Provincial People＇s Hospital, Chengdu , Sichuan 610072, China)

机构地区：[1]四川省医学科学院.四川省人民医院,四川成都610072

出　　处：《四川医学》2018年第4期404-408,共5页Sichuan Medical Journal

摘　　要：目的探讨经皮微波消融治疗复发性小肝细胞肝癌的近期疗效比较。方法收集同期经皮微波消融和再次肝切除治疗复发性小肝细胞性肝癌的临床资料,比较相关临床指标。结果两组病例在年龄、性别、Child-Pugh分级、肝硬化、肿瘤个数及术后复发时间等方面均无统计学差异(均P>0.05)。微波消融组术后下床时间、进食时间、疼痛评分和术后住院天数指标,均好于再次肝切除组(均P<0.05)。微波消融组术后并发症发生少,不增加严重并发症发生率。两组病例术后无瘤生存率(χ~2=0.001,P=0.975)及累积生存率(χ~2=0.090,P=0.764)比较无统计学差异。结论经皮微波消融可作为复发性小肝细胞肝癌的首选治疗方式,是一种安全、有效的方法。Objective To investigate the short-term efficacy of percutaneous microwave ablation in the treatment of recurrent small hepatocellular carcinoma.Methods We collected the clinical data of simultaneous percutaneous microwave ablation and rehepatectomy in the treatment of recurrent small hepatocellular carcinoma and compared the relevant clinical indicators.Results There was no significant difference in age,sex and Child-Pugh grade,liver cirrhosis,tumor number and recurrence time between the two groups（ all P〈0. 05）.After operation,the time of getting out of bed,feeding time,pain score and postoperative hospitalization in microwave ablation group were better than those in rehepatectomy group（ all P〈0. 05）. In microwave ablation group,the incidence of postoperative complications was less,and the incidence of severe complications was not increased.There was no statistical difference between the two groups in tumor free survival rate（χ~2 = 0. 001,P = 0. 975） and cumulative survival rate（χ~2 = 0. 090,P =0. 764）.Conclusion Percutaneous microwave ablation can be the first choice for the treatment of recurrent small hepatocellular carcinoma,which is a safe and effective method.

关 键 词：复发肝癌 微波消融 再次肝切除术 疗效 

分 类 号：R61[医药卫生—外科学]