2008-2017年中国生殖器疱疹流行特征分析  

Epidemiologic features of genital herpes in China from 2008 to 2017

作　　者：岳晓丽[1] 龚向东[1] 李婧[1] 王雅洁[1] Yue Xiaoli;Gong Xiangdong;Li ring;Wang Yajie(Division of Sexually Transmitted Disease Epidemiology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Sexually Transmitted Disease Control, China Center for Disease Control and Prevention, Nanjing 210042, China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所中国疾病预防控制中心性病控制中心性病流行病室,南京210042

出　　处：《中华皮肤科杂志》2018年第5期332-336,共5页Chinese Journal of Dermatology

基　　金：中国医学科学院医学与健康科技创新工程重大协同创新项目（CIFMS-2017-12M-1-017）

摘　　要：目的了解2008--2017年全国生殖器疱疹流行特征，为制定防控对策提供依据。方法应用描述性流行病学方法对2008--2017年全国105个国家性病监测点报告的生殖器疱疹病例资料进行“三间分布”分析。。结果生殖器疱疹报告发病率从2008年的8．30／10万下降到2017年的6．14／10万，年均下降3．29％。不同监测点报告发病率差异较大，最高可达113．51／10万，最低〈1／10万。高发地区主要为广东、广西、海南、浙江、福建、重庆和湖北，报告发病率较低的地区主要为华北和中部地区，少数农村监测点无病例报告。2016年女性报告发病率略高于男性，其他年份男性均高于女性，男女性别比由2008年的1．77：1下降至2017年的1．03：1。生殖器疱疹高发年龄段为20—39岁的性活跃人群，以25—34岁年龄组报告发病率最高（17．84／10万～26．89／10万）。综合医院报告病例数最多，占58．13％。76．52％，其次为皮肤性病专科医院、妇科医院和妇幼保健院。结论虽然中国生殖器疱疹报告发病率整体呈下降趋势，但在广东、广西、海南、浙江、福建、重庆和湖北发病率仍较高，应根据各地疾病流行特点有针对性地采取不同的防治措施。Objective To investigate epidemiological features of genital herpes in China from 2008 to 2017, and to provide scientific evidences for developing control strategies. Methods A descriptive epidemiological study was conducted to analyze personal, spatial and temporal distribution of genital herpes cases reported from 105 sexually transmitted disease （STD） surveillance sites between 2008 and 2017. Results The reported incidence of genital herpes decreased from 8.30 per 100 000 in 2008 to 6.14 per 100 000 in 2017, with an average annual decline rate of 3.29%. There was marked variation in the reported incidence of genital herpes among different STD surveillance sites, with a range from 〈 1 per 100 000 to 113.51 per I00 000. The reported incidence was relatively high in Guangdong, Guangxi, Hainan, Zhejiang, Fujian, Chongqing and Hubei, but low in north China and central China. In addition, no cases were reported at a few sites in rural areas. The reported annual incidence was higher in females than in males in 2016, but higher in males than in females in the other years. The ratio of male to female cases decreased from 1.77 ： 1 in 2008 to 1.03： I in 2017. Among all the age groups, the sexually active population aged 20- 39 years showed high reported incidence of genital herpes, with the highest reported incidence observed in the group aged 25- 34 years （range, 17.84/100 000- 26.89/100 000）. Among all kinds of medical institutions, general hospitals had the largest number of reported cases of genital herpes （range, 58.13% - 76.52% ）, followed by specialized dermatovenereology hospitals, gynecology hospitals and maternal and child health （MCH） hospitals. Conclusions Although the overall reported incidence of genital herpes shows a downward trend, the reported incidence is high in Guangdong, Guangxi, Hainan, Zhejiang, Fujian, Chongqing and Hubei. Therefore, different prevention strategies are needed to be developed according to the epidemiological features.

关 键 词：生殖器疱疹 发病率 人群监测 流行病学 

分 类 号：R752.1[医药卫生—皮肤病学与性病学]