中国2010年和2015年胎传梅毒空间分布特征  

Spatial distribution characteristics and patterns of congenital syphilis in 2010 and 2015 in China

作　　者：王雅洁[1] 龚向东[1] 岳晓丽[1] 李婧[1] Wang Yajie;Gong Xiangdong;Yue Xiaoli;Li Jing(Division of Sexually Transmitted Disease Epidemiology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, National Center for Sexually Transmitted Disease Control, China Center for Disease Control and Prevention, Nanjing 210042, China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所中国疾病预防控制中心性病控制中心性病流行病室,南京210042

出　　处：《中华皮肤科杂志》2018年第5期337-340,共4页Chinese Journal of Dermatology

基　　金：中国医学科学院医学与健康科技创新工程重大协同创新项目（CIFMS-2017-12M-1-017）

摘　　要：目的分析我国胎传梅毒空间分布特征，为制定精准的梅毒母婴传播预防策略提供依据。方法收集2010年、2015年全国31个省、自治区、直辖市报告的胎传梅毒病例数据，使用地理信息系统ArcGIS10．0软件进行胎传梅毒疫情的探索性空间分析。结果2015年全国共报告7251例胎传梅毒，较2010年（12084例）下降了40．00％。全局空间自相关分析结果显示，2010年和2015年全国县区级胎传梅毒报告病例数全局MoranI指数分别为0．46和0．37，均呈显著的空间正相关，2015年胎传梅毒疫情的空间聚集性低于2010年。通过局部空间自相关分析输出我国县区级胎传梅毒疫情分布热点地图：2010年呈现3个核心区域，主要分布于西南部分地区，包括重庆、四川东部和贵州北部；华东部分地区，包括江苏南部、浙江和福建北部；华南和华中部分地区，包括广西、广东和湖南中东部，共发现207个热点县区（病例数〉12）；2015年呈现5个核心区域，主要分布于西北地区的新疆西部；青海中东部；西南与华中部分地区，包括四川、重庆、贵州和湖南；华东部分地区，包括江苏与安徽；华南与华东部分地区，包括广东与福建，共发现72个热点县区（病例数〉12）。结论2015年浙江、上海、广东、广西、四川、重庆等地的胎传梅毒疫情热点县区数量明显少于2010年，预防梅毒母婴传播工作初见成效。现阶段我国胎传梅毒疫情热点县区主要分布于新疆西部、青海中东部、四川I、重庆、贵州等地，今后应重点加强这些地区的梅毒母婴传播预防工作。Objective To investigate the spatial distribution characteristics and patterns of congenital syphilis in China, and to make suggestions and recommendations for precise prevention of mother- to-child transmission of syphilis. Methods The geographic information system software ArcGIS 10.0 was used to conduct exploratory spatial data analysis on the basis of congenital syphilis cases reported from 31 provinces, autonomous regions and municipalities directly under the central government in 2010 and 2015. Results In 2015, a total of 7 251 congenital syphilis cases were reported, which decreased by 40.00% compared with the case number in 2010 （12 084 cases）. The global spatial autocorrelation analysis revealed a positive spatial autocorrelation in the number of reported cases at the county level in China between 2010 and 2015, with Global Moran＇s I indices of 0.46 and 0.37, respectively. The degree of spatial clustering of congenital syphilis was lower in 2015 than in 2010. The local spatial autocorrelation analysis was further performed to output the hot-spot mappings of congenital syphilis at the county level in 2010 and 2015. In 2010, 207 hot-spot counties with a high number of congenital syphilis cases （〉 12 cases） were identified, and these counties were mainly distributed in 3 core areas including southwest China （Chongqing, eastern Siehuan and northern Guizhou）, eastern China （southern Jiangsu, Zhejiang and northern Fujian）, and southern and central China （Guangxi, Guangdong and mid-east Hunan）. In 2015, 72 hot-spot counties with a high number of congenital syphilis cases （〉 12 cases）were identified, and mainly distributed in 5 core areas including northwest China （western Xinjiang）, mid-east Qinghai, southwest and central China （Sichuan, Chongqing, Guizhou and Hunan）, eastern China （Jiangsu, Anhui）, and southern China and eastern China （Guangdong and Fujian）. Conclusions In Zhejiang, Shanghai, Guangdong, Guangxi, Sichuan and Chongqing, the number of hot-spot countie

关 键 词：胎传梅毒 病例报告 地理信息系统 探索性空间分析 空间自相关 热点地图 

分 类 号：R759.15[医药卫生—皮肤病学与性病学]