系统性红斑狼疮患者皮肤黏膜损害139例分析  

Clinical analysis of 139 systemic lupus erythematosus cases with cutaneous and mucosal lesions

作　　者：郭雨凡[1] 武剑[1] 沈晓雯 刘楚 付梦真 GUO Yufan;WU Jian;SHEN Xiaowen;et al(Department of Rheumatology , Affiliated First Hospital, Soochow University, Suzhou 215006, CHINA)

机构地区：[1]苏州大学附属第一医院风湿科,江苏215006

出　　处：《江苏医药》2018年第4期429-431,共3页Jiangsu Medical Journal

摘　　要：目的探讨系统性红斑狼疮(SLE)皮肤黏膜损害的临床特点。方法回顾性分析210例SLE患者的临床资料,探讨皮肤黏膜损害与其他脏器受累的关系。结果 210例中,有皮肤黏膜损害者139例,最为多见的是蝶形红斑80例(57.6%)、脱发38例(27.3%)、冻疮样皮疹36例(25.9%)、指/趾红斑29例(20.9%)。与无皮肤黏膜损害患者比较,有皮肤黏膜损害者神经系统受累比例高,心脏受累、浆膜炎和血红蛋白降低比例较低(P<0.05)。结论 SLE患者皮肤黏膜损害发生率较高,且与其他脏器受累有一定关系。Objective To analyze clinical characteristics of systemic lupus erythematosus（SLE） patients with cutaneous and mucosal lesions. Methods Clinical data of 210 SLE patients were retrospectively analyzed and the relationship of cutaneous and mucosal lesions and other organs involvement was investigated. Results Of 210 cases, 139 patients had cutaneous and mucosal lesions. The most commom cutaneous and mucosal lesions included butterfly erythema in 80 cases（57.6%）, alopecia in 38 cases（27.30//oo）,chilblain rash in 36 cases（25.9~/oo） and fingers or toes erythema in 29 cases（20.9%）. Compared to SLE patients without cutaneous and mucosal lesions, the SLE patients with cutaneous and mucosal lesions had a higher percentage of nervous system involvement and lower percentages of cardiac involvement, serositis and patients have higher incidence of cutaneous and involvements. hemoglobin reduction（P〈0. 05）. Conclusion SLE mucosal lesions, which is related to other organs

关 键 词：系统性红斑狼疮 

分 类 号：R593[医药卫生—内科学]