超声引导射频消融治疗非恶性甲状腺结节  

Effect of ultrasound guided radiofrequency ablation in the treatment of non malignant thyroidnodules

作　　者：高腾[1] 于璐[1] 李红光[1] 张振华[1] 段少傅 张连仲[1] 苏自杰 Teng;Yu Lu;Li Hongguang;Zhang Zhenhua;Duan Shaofu;Zhang Lianzhong;Su Zijie(Henan Provincial People＇s Hospital, Zhengzhou 450003, Chin)

机构地区：[1]河南省人民医院,郑州450003

出　　处：《中国实用医刊》2018年第7期14-17,共4页Chinese Journal of Practical Medicine

基　　金：河南省2016年科技发展计划（162102310177）;2017年河南省医学科技攻关项目（201702225）

摘　　要：目的探讨经超声引导下射频消融治疗不同类型非恶性甲状腺结节的临床效果。方法对经穿刺细胞病理学证实的非恶性甲状腺结节患者203例（432个结节）在超声引导下采用射频消融技术治疗。观察术后3、6、9、12个月结节消融情况（最大直径、体积减少率）。结果203例患者均完成射频消融治疗，未见严重损伤及并发症。其中术中疼痛15例，血压不同程度升高47例，对症处理后均完成手术；术后短期声音嘶哑4例，均在3个月内完全恢复。消融前结节最大直径（2.97±0.92）cm，最大体积（8.89±3.04）cm3；消融治疗后3、6、9、12个月结节体积逐渐缩小，平均体积分别为（4.86±4.02）、（3.01±2.84）、（2.12±1.51）、（1.55±1.40）cm3，结节中囊性比例高者消融效果优于囊性比例低者。结论超声引导下射频消融治疗非恶性甲状腺结节效果确切、安全且无瘢痕。Objective To investigate the clinical effects of ultrasound guided radiofrequency ab- lation on the treatment of different types of non malignant thyroid nodules. Methods A total of 203 patients with non malignant thyroid nodules （432 nodules） confirmed by biopsy cell pathology were treated by ultrasound guided radiofrequency ablation. Ablation results （ maximum diameter of nodule and the vol- ume reduction rate） were observed and recorded at 3, 6, 9 and 12 months after ablation. Results Two hundred and three patients all successfully received completed radiofrequency ablation, with no severe in- jury or complications. Among the 203 patients, 15 cases had intraoperative pain, 47 cases had intraoper- ative blood pressure increase with different intensity and were cured after symptomatic treatment to com- plete the operation; 4 cases had short-term hoarseness after operation and recovered completely within 3 months. Before ablation, the maximum diameter of nodule was （2. 97 ± 0. 92） cm, and maximum vol- ume was （8. 89 ±3.04）cm3; nodule volume gradually reduced 3, 6, 9, 12 months after ablation treat- ment, and he average volume was （4.86 ±4.02）cm3, （3.01 ±2.84）cm3, （2.12 ± 1.51）cm3, （ 1.55 ± 1.40） cm3 , respectively. Ablation effects on patients with high proportion of cystic nodules was better than that of patients with low proportion of cystic proportion. Conclusions Ultrasound guided ra- diofrequency ablation is a reliable treatment method for non malignant thyroid nodules, which is safe and searless.

关 键 词：超声引导射频消融 甲状腺结节 治疗效果 

分 类 号：R653[医药卫生—外科学]