肾脏替代治疗在公民死亡器官捐献供肾移植中的临床效果  

Clinical effects of renal replacement therapy for kidney transplantation from donation after citizen′s death

作　　者：丁利民[1] 罗文峰[1] 黄小梅[1] 徐志丹[1] 李新长[1] DING Limin;LUO Wenfeng;HUANG Xiaomei;XU Zhidan;LI Xinchang(Jiangxi Provincial People＇s Hospital, Nanchang 330006, Chin)

机构地区：[1]江西省人民医院,南昌330006

出　　处：《实用医学杂志》2018年第8期1273-1277,共5页The Journal of Practical Medicine

基　　金：江西省科技厅重点研发计划(编号:20151BBG70069;20161BBG70121)

摘　　要：目的探讨肾脏替代治疗在公民死亡器官捐献(DCD)供肾移植中的临床应用。方法选择2013年1月至2016年12月期间DCD供肾移植术后41例行肾脏替代治疗受者,其中腹膜透析14例、间断性血液透析(IHD)21例、连续肾脏替代疗法(CRRT)6例,回顾性分析3种肾脏替代治疗方式的治疗效果及并发症。结果 3组透析治疗后血BUN、Crea、血钾的浓度较治疗前明显下降(P<0.05),IHD及CRRT组治疗前后Crea、BUN差值高于腹膜透析组(P<0.05),IHD与CRRT组比较差异无统计学意义(P>0.05)。结论 DCD供肾移植术后根据受者病情选择恰当的肾脏替代治疗方式是保护移植肾功能甚至挽救患者生命的关键。Objective To explore the clinical application of renal replacement therapy in renal transplan-tation from donation after citizen′s death（DCD）. Methods A total of 41 cases of the patients with renal replace-ment therapy after renal transplantation from DCD from January 2013 to December 2016 were involved,of which14 cases received peritoneal dialysis,21 intermittent hemodialysis（IHD）and 6 continuous renal replacement ther-apy（CRRT）.The therapeutic effect and complications of three renal replacement therapies were retrospectively ana-lyzed. Results After dialysis treatment,the concentration of blood BUN,Crea,and potassium was significantlylower than that before the treatment（P〈0.05）;the difference of Crea and BUN before and after the treatment inIHD and CRRT group was higher than that in peritoneal dialysis group（P〈0.05）but there was no statistically sig-nificant difference between IHD and CRRT group（P〈0. 05）. Conclusion The renal replacement after kidneytransplantation from DCD should be based on the patient′s condition,which is the key to protect their kidneys evento save patients′ lives.

关 键 词：公民死亡器官捐献 肾移植 肾脏替代治疗 临床效果 并发症 

分 类 号：R699.2[医药卫生—泌尿科学]