控制性超促排卵中出现早发黄体生成素峰后加倍使用拮抗剂的效果——1例报道  

Effect of double use of gonadotropin-releasing hormone antagonist after premature luteinizing hormone surge during controlled ovarian hyperstimulation cycles

作　　者：李佳琛 邹红艳[1] Li Jiachen;Zou Hongyan(Reproductive Center, Shenzhen Luohu People＇s Hospital, Shenzhen 518001, China)

机构地区：[1]深圳市罗湖区人民医院生殖医学科,518001

出　　处：《中华生殖与避孕杂志》2018年第3期241-243,共3页Chinese Journal of Reproduction and Contraception

摘　　要：目的探讨在控制性超促排卵中早发黄体生成素(LH)峰对卵泡发育及胚胎质量的影响。方法分析同一患者2个促排卵周期的获卵数及胚胎质量。结果促排卵过程中出现的早发LH峰在加倍使用拮抗剂后对卵泡发育及胚胎质量未见明显影响。结论单一性早发LH峰出现时给予加量拮抗剂控制LH水平下降至安全范围之内,可挽救该助孕周期,获得较优质的胚胎。Objective To discuss the impact of premature luteinizing hormone （LH） surge on the follicle development and embryo quality during controlled ovarian hyperstimulation （COH）. Methods The number of retrieved ooeytes and embryo quality in two different COH cycles on the same patient were analyzed. Results The impact of premature LH surge during COH cycles was not significantly different on the follicle development and embryo quality after the double-dose gonadotropin-releasing hormone （GnRH） antagonist administration. Conclusion A double-dose of GnRH-antagonist administration could decrease the level of single premature LH surge to safe range, which might rescue this COH cycle and get high-quality embryos.

关 键 词：拮抗剂方案 早发黄体生成素(LH)峰 胚胎质量 

分 类 号：R714.8[医药卫生—妇产科学]