良性前列腺增生患者前列腺突入膀胱程度与膀胱出口梗阻的相关性研究  

Correlation between degree of prostatic protrusion into bladder and bladder outlet obstruction in patients with different degrees of prostatic hyperplasia

作　　者：李保国[1] 林毅枢 李鑫[1] 张钢[1] 唐科伟[1] 王文生[1] LI Baoguo;LIN Yishu;LI Xin;ZHANG Gang;TANG Kewei;WANG Wensheng(Department of Urology,Beijing Haidian Hospital, Peking University, Beijing 100080,China)

机构地区：[1]北京市海淀医院/北京大学第三医院海淀院区泌尿外科,100080

出　　处：《疑难病杂志》2018年第5期490-493,共4页Chinese Journal of Difficult and Complicated Cases

基　　金：北京市海淀医院/北京大学第三医院海淀院区院级项目(KYM2015011)

摘　　要：目的分析不同程度良性前列腺增生(BPH)患者前列腺突入膀胱程度(IPP)与膀胱出口梗阻(BOO)的相关性。方法选择2015年8月—2017年5月因下尿路症状(LUTS)在北京市海淀医院/北京大学第三医院海淀院区泌尿外科就诊的BPH患者191例作为研究对象。测定患者前列腺体积(TPV)、IPP,并进行尿流动力学检查。根据TPV大小将191例患者分为3组,轻度组(TPV<50 ml)94例,中度组(50 ml≤TPV≤75 ml)61例和重度组(TPV>75 ml)34例。分析不同程度BPH患者中IPP与膀胱出口梗阻指数(BOOI)相关性。结果轻度组TPV与BOOI无显著相关性(P>0.05),IPP与BOOI有显著相关性(P<0.05);中度与重度组BPH患者中,TPV、IPP均与BOOI有显著相关性(P<0.05)。轻度组IPP>10 mm的患者BOO阳性率显著高于全组患者(74.2%vs.28.7%,χ~2=20.083,P<0.01);中度组IPP>10 mm的患者BOO阳性率显著高于全组患者(82.5%vs.62.3%,χ~2=5.027,P<0.05);重度组IPP>10 mm的患者BOO阳性率与全组患者差异无统计学意义(93.7%vs.88.8%,χ~2=0.498,P>0.05)。结论IPP的测定对判断BPH患者BOO有着重要的参考意义,尤其适用于轻度、中度BPH患者。Objective To explore the significance of IPP measurement in judging bladder outlet obstruction （BOO） in patients with different degrees of BPH. Methods 191 cases BPH patients with LUTS treated in the department of Urology in Haidian Hospital of Peking University were chosen as study objects. The TPV,IPP,and uro-dynamics of the 191 BPH patients were measured. According to the TPV size,the 191 cases were divided into 3 groups,mild group （TPV 〈 50 ml）,moderate group （50 ml ≤ TPV ≤ 75 ml） and severe group （TPV 〉 75 ml）. Then the correlation between IPP and BOOI in patients with different degrees of BPH was analyzed. Results In the mild group,there was no significant correlation between TPV and BOOI （ P 〉0.05）,but there was a significant correlation between IPP and BOOI （ P 〈 0.05）; In the moderate and severe group,TPV and IPP were significantly correlated with BOOI （ P 〈 0.05）,but the correlation coefficient between IPP and BOOI was higher. In mild group,the positive rate of BOO in patients with IPP 〉10 mm was significantly higher than that in the whole group（74.2% vs. 28.7%,χ 2 = 20.083, P 〈0.01）; In the moderate group,the positive rate of BOO in patients with IPP 〉10 mm was significantly higher than that in the whole group（82.5% vs. 62.3%,χ 2 = 5.027, P 〈0.05）;In the severe group,there was no significant difference in the positive rate of BOO between the patients with IPP 〉10 mm and the whole group（93.7% vs. 88.8%,χ 2 = 0.498, P 〉0.05）. Conclusion The determination of IPP has important reference value for judging bladder outlet obstruction （BOO） in patients with BPH,especially for mild and moderate BPH patients.

关 键 词：前列腺增生 前列腺体积 突入膀胱程度 膀胱出口梗阻 

分 类 号：R697.3[医药卫生—泌尿科学]