一起学校诺如病毒聚集性疫情的病例对照调查  

A case-control investigation on Norovirus aggregation in school

作　　者：刘红联 汤泓[2] 夏仪[2] 梁倩倩 方延 庄建林[2] LIU Hong-lian;TANG Hong;XIA Yi;LIANG Qian-qian;FANG Yan;ZHUANG Jian-lin(Changning District Xinhua Community Heath Center, Shanghai 200052, China;Changning District Center of Diseases Control and Preven- tion, Shanghai 200051, China)

机构地区：[1]上海市长宁区新华社区卫生服务中心,上海200052 [2]上海市长宁区疾病预防控制中心,上海200051

出　　处：《上海预防医学》2018年第4期304-306,共3页Shanghai Journal of Preventive Medicine

基　　金：上海市长宁区科委卫生应急项目(CNKW2016Y18)

摘　　要：【目的】对上海市某中学发生的一起诺如病毒感染性腹泻聚集性疫情进行调查和分析。【方法】采用病例对照的调查方法,将所有病例作为病例组,将同班级内未发病学生作为对照组,以问卷调查的形式进行回顾性调查。同时采集部分病例标本进行实验室检测。【结果】本次疫情共有19名学生出现呕吐、腹泻;病例对照调查提示学生秋游时食用的景区路边摊自制食品为可疑暴露因素(P=0.001);7名患者粪便中检出诺如病毒核酸GⅡ型。【结论】本次疫情为一起诺如病毒感染性腹泻聚集性疫情,可疑病因为学生秋游时食用的景区路边摊自制食品。[Objective] To investigate and analyze the cause of an outbreak caused by Norovirus which happened at a middle school in Shanghai. [Methods]Case-control investigation method was used. Patients with gastroenteritis symptoms were defined as case group,and those without symptoms in the same class as control group. Retrospectives epidemiological investigation had been applied. Biological specimens of cases were tested in laboratory. [Results] There were a total of 19 students with vomit and（ or） diarrhea symptoms. Case-control study showed that the risk factor might be one kind of homemade food sold from the stalls at the scenic spot（ P = 0. 001）,Norwalk virus RNA（ type GⅡ） were detected from stool specimens of 7 patients. [Conclusion]The outbreak was probably caused by Norovirus,and the suspicious risk factor was contamination of homemade food from stalls at the scenic spot.

关 键 词：诺如病毒 聚集性疫情 病例对照 调查 

分 类 号：R183[医药卫生—流行病学]