疏风解毒胶囊联合常规治疗上气道咳嗽综合征的疗效观察  

Curative Effect of Shufeng Jiedu Capsules Combined with Conventional Treatment on Upper Airway Cough Syndrome

作　　者：吴启富[1] 赵将[2] 吴江华 Wu Qifu;Zhao Jiang;Wu Jianghua(Huaying Maternal and Child Health Hospital, Sichuan Huaying 638699, China;Department of Pediatrics, Mianyang People＇s Hospital)

机构地区：[1]华蓥市妇幼保健院,四川华蓥638699 [2]绵阳市人民医院儿科

出　　处：《中国药师》2018年第5期856-858,共3页China Pharmacist

摘　　要：目的:探讨疏风解毒胶囊治疗上气道咳嗽综合征(UACS)的临床疗效和安全性。方法:有基础鼻或鼻窦疾患的UACS患者55例随机分成观察组(n=28)和对照组(n=27)。对照组予氯雷他定片10 mg qd;布地奈德鼻喷剂128μg,喷鼻,bid;罗红霉素分散片0.15 g qd。观察组在对照组基础上加用疏风解毒胶囊40 mg·kg^(-1),po,tid。两组均连续用药4周。观察两组患者治疗前后各项症状积分变化及药品不良反应,评价两组疗效。结果:观察组总有效率达85.71%,明显优于对照组的70.37%(P<0.05)。两组患者鼻部症状和咳嗽症状均较治疗前明显改善(P<0.05),且观察组各项症状积分均优于对照组(P<0.05)。结论:常规治疗方案加用疏风解毒胶囊治疗UACS能明显提高临床疗效。Objective： To observe the clinical effect of Shufeng Jiedu capsules combined with the conventional treatment on upper airway cough syndrome （UACS）. Methods： Totally 55 patients with UACS and basic nasal or sinus diseases were randomly divided into two groups： the treatment group （n = 28） and the control group （n = 27）. The treatment group was treated with Shufeng Jiedu capsules combined with the regimen for the control group, 40 mg · kg-1 , 3 times a day, and the regimen for the control group was as follows： loratadine tablets, 10 mg,qd, budesonide nasal spray hormone 128 μg, bid, roxithromycin dispersible tablets, 0.15 g,qd. The treatment course was 4 weeks. The changes of symptom scores were observed and the adverse reactions were recorded to compare the efficacy between the groups. Results： The total effective rate of the treatment group was 85.71%, which was significantly higher than that of the control group （75.37%, P 〈 0.05）. The cough and nasal symptoms were notably improved in the two groups after the treatment（P 〈 0.05 ）, and all the symptom scores in the treatment group were better than those in the control group （P 〈 0.05）. Conclusion： Shufeng Jiedu capsules combined with the conventional treatment can improve the efficacy in the treatment of UACS.

关 键 词：疏风解毒胶囊 上气道咳嗽综合征 慢性咳嗽 疗效 

分 类 号：R286[医药卫生—中药学]