Adherence to pharmacological and non-pharmacological treatment of frail hypertensive patients  

作　　者：Beata Jankowska-Polanska Karolina Zameta Izabella Uchmanowicz Anna Szymanska-Chabowska Donald Morisky Grzegorz Mazur 

机构地区：[1]Department of Clinical Nursing, Wroclaw Medical University, Wroclaw, Poland [2]Department of lnternal Medicine, Occupational Diseases, Hypertension and Oncology, Wroclaw Medical University, Wroclaw, Poland [3]Department of Community Health Sciences, UCLA Fielding School of Public Health, Los Angeles, USA

出　　处：《Journal of Geriatric Cardiology》2018年第2期153-161,共9页老年心脏病学杂志（英文版）

摘　　要：Objective To investigate the relationship between frailty syndrome （FS） and adherence to pharmacological and non-pharmacological treatment for hypertension. Methods The study included 100 patients diagnosed with hypertension and treated with one or more hypotensive drugs. Results Frail patients obtained low scores （4.1 ± 2.0） for adherence to pharmaceutical treatment of hypertension, while non-frail patients obtained moderate scores （6.1 ± 2.1）. Non-frail patients had higher scores in two out of four domains of the Health Behavior Inventory （HBI）： positive mental attitudes （3.6 ± 0.4 vs. 3.2 ± 0.5; P = 0.006） and health practices （3.6 ± 0.5 vs. 3.2 ± 0.5; P 〈 0.03）; as well as higher global scores （HBI raw score）： 83.3 ±10.6 vs. 77.3 ± 9.5; P 〈 0.03. Multiple regression analysis showed that frailty syndrome （FS） was a statistically significant independent determinant of worse adherence to pharmacological treatment （β= -0.27; P 〈 0.001） and health behaviors （β = -0.10; P = 0.036）. Education was a statistically significant independent determinant of better adherence to pharmacological treatment （β = 0.82; P = 0.012）, while net income positively affected health behaviors as measured by the HBI （β = 0.39; P = 0.046）. Conclusions FS is a significant independent factor contributing to worse adherence to pharmacological and non-pharmacological treatment of hypertension. Better education significantly improves patients＇ adherence to the prescribed pharmacological treatment, while a good financial standing evidenced by high net income is a determinant of better adherence to health-related behaviors recommended in hypertension treatment.

关 键 词：ADHERENCE ELDERLY Frailty syndrome Non-pharmacological treatment 

分 类 号：S858[农业科学—临床兽医学] TQ461[农业科学—兽医学]