Gα亚基基因与黑色素合成的研究进展  

Research Progress in Gα Subunit Gene and Melanin Synthesis

作　　者：翁吉梅 罗铮 徐伟[1] 封竣琪 蔡惠芬[1] 罗卫星[1] 陈说 WENG Jimei;LUO Zheng;XU Wei;FENG Junqi;CAI Huifen;LUO Weixing;CHEN Shuo(Key Laboratory of Animal Genetics,Breeding and Reproduction in the Plateau Mountainous Region , Ministry of Education, College of Animal Science, Guizhou University, Guiyang, Guizhou 550025;Renhuai Stock Seed Farm of Qianbei Ma Goat, Renhuai, Guizhou 564500, China)

机构地区：[1]贵州大学高原山地动物遗传育种与繁殖省部共建教育部重点实验室/动物科学学院,贵州 贵阳 550025 [2]贵州省仁怀市黔北麻羊原种场，贵州 仁怀 564500

出　　处：《贵州农业科学》2018年第4期9-13,共5页Guizhou Agricultural Sciences

基　　金：贵州省科技计划项目[黔科合NY(2015)3010-1];贵州省科技计划项目(ZJNLT-RH-RHKJJ-002)子项目"仁怀市省级可持续发展实验区建设"

摘　　要：Gα亚基基因是G蛋白信号调节途径的中心结构,也是激活G蛋白信号传导的关键亚基,在不同组织细胞中能转导不同的信号,完成不同的生物学功能。为全面了解Gα亚基基因在色素沉积方面的作用,对Gα亚基基因的结构、功能、转导机制、黑色素的合成、Gα亚基基因在临床医学和动物色素沉积等方面的最新研究进展进行了综述。Gα subunit gene is the central structure of G protein signal regulatory pathway and the key subunit to activate G protein signal transduction for realizing different biological functions by transducing different signals in cells of different tissues.The recent research progress in Gα subunit gene is reviewed from six aspects of structure,function,transduction mechanism,melanin synthesis,clinical medicine and animal pigmentation to understand the effect of Gα subunit gene in pigmentation overall.

关 键 词：Gα亚基 Gnaq基因 Gna11基因 色素沉积 

分 类 号：S831[农业科学—畜牧学]