肝脏局灶性病变的实时三维超声造影成像质量的影响因素分析  

Image quality of dynamic three-dimensional contrast-enhanced ultrasonography in focal liver lesions: an analysis of influencing factors

作　　者：卢颖[1] 黄光亮[1] 郑艳玲[1] 刘保娴 陈勉妮[1] 谢晓燕[1] Lu Ying;Huang Guangliang;Zheng Yanling;Liu Baoxian;Chen Mianni;Xie Xiaoyan(Department of Medical Ultrasonic, Institute of Ultrasonic Diagnosis and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-sen Uaiversity, Guangzhou 510080, China)

机构地区：[1]中山大学附属第一医院超声科中山大学超声诊断与介入超声研究所,广州510080

出　　处：《中华普通外科学文献（电子版）》2018年第2期106-110,共5页Chinese Archives of General Surgery(Electronic Edition)

基　　金：国家自然科学基金资助项目(81501493;81530055)

摘　　要：目的探讨实时三维超声造影(4D-CEUS)成像质量的影响因素。方法回顾性分析2013年6月至2014年3月经病理及临床确诊的151例肝脏局灶性病变(FLLs)患者的影像资料,对其4D-CEUS成像质量进行评分并分析影响成像质量的因素。结果 (1)4D-CEUS检查时慢推造影剂组得到的纯动脉相最长,平均时间为(5.17±1.03)s,成像质量优于常规团助法(统计值88.868,P=0.000)。(2)151例FLLs的4D-CEUS动脉期成像质量评价1级82例(54.3%),2级17例(11.3%),3级25例(16.6%),4级27例(17.9%)。151例病变呈高、等、低或无增强者分别有119例(78.8%)、6例(4.0%)和26例(17.2%)。病变直径、位置、扫查路径、有无干扰因素、有无伪影、动脉期增强程度对4D-CEUS的成像质量有显著影响(统计值为-2.455、-2.198、-2.428、-5.575、-6.469、43.060,均P<0.05)。结论 4D-CEUS成像质量的影响因素有注药方式,病变直径、位置及增强方式,扫查路径、扫查过程中有无伪影,有无膈肌、肋骨、心脏、大血管等成像干扰因素。Objective To explore 4 D-CEUS methodologies and the factors affecting image quality. Methods 4 D-CEUS data of one hundred and fifty-one focal liver confirmed by pathology and clinical follow-up from the First Affiliated Hospital of Sun Yat-sen University were respectively analyzed. The image quality was scored and influencing factors were analyzed. Results（1） The injection methods of 4 D-CEUS had significant influence on the imaging quality of 4 D-CEUS, while slow injecting contrast agents without saline could prolong pure arterial pulse, mean time was（5.17±1.03） s, with image quality superior to conventional bolus（statistical value 88.868, P=0.000）.（2） The image quality of 4 D-CEUS in the arterial phase of 151 FLLs was divided into 4 grades, with 82 cases（54.3%） in grade 1, 17 cases（11.3%）in grade 2, 25 cases（16.6%） in grade 3, 27 cases（17.9%） in grade 4. The number of lesions showing hyper-enhancement, iso-enhancement, hypo-enhancement was 119（78.8%）, 6（4.0%） and 26（17.2%）, respectively. Location of lesions, sizes, scanning path, interference, and the artifacts had significant influences on the image quality of 4 D-CEUS（statistical values-2.455,-2.198,-2.428,-5.575,-6.469, 43.060, all P0.05）. Conclusion The image quality of 4 D-CEUS is affected by the method of injection, sizes of lesions, location, blood supply, scanning path, the presence of artifacts, and the presence of interference.

关 键 词：肝疾病 成像 三维 超声检查 肝脏局灶性病变 

分 类 号：R445.1[医药卫生—影像医学与核医学] R575[医药卫生—诊断学]