基于数据挖掘的穴位贴敷治疗失眠的选穴与用药规律  

Investigation of Selection of Acupoints and Chinese Herbs for Acupoint Application in Treating Insomnia Based on Data Mining

作　　者：谢晨[1,2] 黄琴峰[1] 杨秋红 邴兴红[4] 于心同[2] 杨文佳[2] 陈云飞[2] XIE Chen;HUANG Qin-Feng;YANG Qiu-Hong;BING Xing-Hong;YU Xin-Tong;YANG Wen-Jia;CHEN Yun-Fei(Shanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China;Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine , Shanghai200437, China;Shanghai Jiangwan Hospital of Hongkou District, Shanghai 200434, China;g. Shanghai Jiading District Hospital of Traditional Chinese Medicine, Shanghai 201899, Chin)

机构地区：[1]上海市针灸经络研究所,上海200030 [2]上海中医药大学附属岳阳中西医结合医院,上海200437 [3]上海市虹口区江湾医院,上海200434 [4]上海市嘉定区中医医院,上海201899

出　　处：《广州中医药大学学报》2018年第3期423-429,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然基金青年项目(编号:81503631);上海中医药大学研究生创新能力培养专项科研项目(编号:JX61.02.03.36);上海市卫生和计划生育委员会科研课题(编号:20174Y0063);上海市卫生和计划生育委员会科研课题(编号:201540375);上海市教委科研创新项目(自然科学类)(编号:14YZ063);上海市科学技术委员会科研计划项目(编号:14401931900)

摘　　要：【目的】通过数据挖掘的方法分析穴位贴敷治疗失眠文献的选穴与用药规律。【方法】采用计算机检索方式检阅中国知网(CNKI)、万方、维普全文数据库(VIP)和Pub Med数据库中有关穴位贴敷疗法治疗失眠的临床研究文献,分析其取穴和所用药物的频次,以总结穴位贴敷治疗失眠文献的选穴与用药规律。【结果】穴位贴敷治疗失眠的文献中所采用的单味中药频次居前5位的是吴茱萸(47次)、肉桂(43次)、酸枣仁(38次)、朱砂(26次)、黄连(22次);药物组合中酸枣仁—夜交藤合用的几率最大,其次为朱砂—琥珀,再次为肉桂—吴茱萸—朱砂。穴位贴敷治疗失眠的文献中所选用的单个穴位频次居前4位的为涌泉(95次)、神阙(38次)、内关(30次)、三阴交(27次),穴位组合中三阴交—肾俞—脾俞合用的几率最大,其次为三阴交—脾俞—足三里,再次为脾俞—足三里—三阴交。【结论】穴位贴敷治疗失眠的常用药物为吴茱萸,经常配伍使用的药物组合为酸枣仁—夜交藤。常用的穴位为涌泉,常用的配伍穴组为三阴交—肾俞—脾俞。Objective To analyze the regularity of selection of acupoints and Chinese herbs for acupointapplication in treating insomnia based on data mining from the related literatures. Methods Literatures of insomniatreated by acupoint application from databases including China National Knowledge Infrastructure（CNKI）,Wanfang,China Biomedical Literature Service System（VIP）and Pub Med were retrieved by using computer,andthe frequency of the acupoints and Chinese herbs for acupoint application in treating insomnia was calculated forexploring the regularity of selection of acupoints and Chinese herbs for acupoint application in treating insomnia.Results The frequently-used leading 5 single herbs were Fructus Evodiae（Wuzhuyu; 47 times）, CortexCinnamomi（Rougui; 43 times）, Semen Zizyphi Spinosae（Suanzaoren; 38 times）, Cinnabaris（Zhusha; 26 times）, and Rhizoma Coptidis（Huanglian; 22 times）; the leading herbal combination was SuanzaorenYejiaoteng（Caulis et Folium Polygoni Multiflori）,and then came Zhusha-Hupo（Ambrum）,Rougui-WuzhuyuZhusha. The frequently-used leading 4 single acupoints were Yongquan（KI1;95 times）,Shenque（CV8;38 times）,Neiguan（PC6;30 times）,and Sanyinjiao（SP6;27 times）;the leading acupoint combination was Sanyinjiao（SP6）-Shenshu（BL23）-Pishu（BL20）,and then came Sanyinjiao（SP6）-Pishu（BL20）-Zusanli（ST36）, Pishu（BL20）-Zusanli（ST36）-Sanyinjiao（SP6）. Conclusion The commonly-used single herb is Wuzhuyu for acupoint application in treating insomnia,and commonly-used herbal combination is SuanzaorenYejiaoteng; the commonly-used single acupoint is Yongquan（KI1）, and the commonly-used acupointcombination is Sanyinjiao-Shenshu-Pishu.

关 键 词：失眠症 穴位贴敷 吴茱萸 酸枣仁 夜交藤 涌泉 文献研究 

分 类 号：R245.9[医药卫生—针灸推拿学]