New coumarin glucopyranosides from roots of Angelica dahurica  

作　　者：Ai-hong Zhao Xiu-wei Yang Ai-hong Zhaoa,b, Xiu-wei Yanga,(a .State Key Laboratory of Natural and Biomimetic Drugs, Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Sdence Center, Peking University, Beijing 100191, China; b .School of Life Sdence and Engineering, Lanzhou University of Technology, Lanzhou 730050, Chin)

机构地区：[1]State Key Laboratory of Natural and Biomimetic Drugs,Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University Health Science Center,Peking University,Beijing 100191,China [2]School of Life Science and Engineering,Lanzhou University of Technology,Lanzhou 730050,China

出　　处：《Chinese Herbal Medicines》2018年第1期103-106,共4页中草药（英文版）

基　　金：The National Natural Science Foundation of China (81473321);Beijing Municipal Natural Science Foundation (7152086);the National Key Technology R & D Program of China (2011BAI07B08;2012BAI29B02)

摘　　要：Objective： To investigate the chemical constituents from the roots of Angelica dahurica.Methods： The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as well as semi-preparative reversed phase HPLC.The chemical structures were identified by spectral data.Results： Ten compounds were isolated and identified as xanthoarnol-3-O-β-d-glucopyranoside（1）,angedahuricoside A（2）,angedahuricoside B（3）,isofraxidin-7-O-β-d-glucopyranoside（4）,fraxidin-8-O-β-d-glucopyranoside（5）,（-）-marmesinin（6）,（2 S,3 R）-3-hydroxymarmesinin（7）,hyuganoside V（8）,daucosterol（9）,and sucrose（10）.Conclusion： Compounds 1 –3 are new ones and compounds 4 –6 and 8 are obtained from title plant for the first time.Objective： To investigate the chemical constituents from the roots of Angelica dahurica.Methods： The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin and Sephadex LH-20 column as well as semi-preparative reversed phase HPLC.The chemical structures were identified by spectral data.Results： Ten compounds were isolated and identified as xanthoarnol-3-O-β-d-glucopyranoside（1）,angedahuricoside A（2）,angedahuricoside B（3）,isofraxidin-7-O-β-d-glucopyranoside（4）,fraxidin-8-O-β-d-glucopyranoside（5）,（-）-marmesinin（6）,（2 S,3 R）-3-hydroxymarmesinin（7）,hyuganoside V（8）,daucosterol（9）,and sucrose（10）.Conclusion： Compounds 1 –3 are new ones and compounds 4 –6 and 8 are obtained from title plant for the first time.

关 键 词：angedahuricoside A angedahuricoside B Angelica dahurica Benth. et Hook. f. ex Franch. et Sav coumarin glucopyranoside xanthoarnol-3-O-β-d-glucopyranoside 

分 类 号：R284.1[医药卫生—中药学]