含碘甲基丙烯酸酯单体的合成及在牙科树脂中的应用  

Synthesis of Iodine-Containing Methacrylate Monomer and its Application in Dental Resin

作　　者：刘芳[1] 朱文彬 何经纬[1] LIU Fang, ZHU Wen-bin ,HE Jing-wei(School of Materials Science and Engineering,South China University of Technology,Guangzhou 510640,Guangdong,Chin)

机构地区：[1]华南理工大学材料科学与工程学院,广东广州510640

出　　处：《华南理工大学学报（自然科学版）》2017年第11期57-62,共6页Journal of South China University of Technology(Natural Science Edition)

基　　金：广东省自然科学基金资助项目(2015A030310338)~~

摘　　要：合成了含碘的甲基丙烯酸酯单体1-(2,3,5-三碘苄基)-N-甲基丙烯酰氧乙基氨基甲酸酯(TIMEC),通过核磁共振氢谱(~1H-NMR)和傅里叶变换红外光谱(FT-IR)确认其结构与设计结构相符.将TIMEC加入到双酚A甲基丙烯酸缩水甘油酯/聚三乙二醇二甲基丙烯酸酯(Bis-GMA/TEGDMA)光固化树脂体系中制备X射线阻射性牙科树脂,研究了单体含量(质量分数)对树脂的相对X射线阻射性(RXO)、双键转化率、体积收缩率、吸水率、溶解率和力学性能的影响;发现:与对照组相比,含TIMEC的树脂的相对X射线阻射性显著提高,吸水率、溶解率以及收缩率也有不同程度的改善;虽然某些配方的树脂的双键转化率和力学性能有所下降,但含20%TIMEC的树脂的各项性能都较为优良,RXO值达113%,双键转化率为57.5%,体积收缩率为6.41%,吸水率为2.65%,溶解率为0.49%,弯曲模量为3 038 MPa,弯曲强度为123.1 MPa,除双键转化率外均优于对照组,表明含TIMEC的树脂具较大的应用潜力.2,3,5-triiodobenzyl methacryloyloxyethylcarbamate（ TIMEC）,an iodine-containing methacrylate monomer,was synthesized,and the consistency of its structure with the designed one was confirmed by means of ~1 HNMR and FT-IR. Then,the monomer was incorporated into the Bis-GMA/TEGDMA light-curable dental resin system to prepare a X-ray radio-opaque dental resin,and the effects of the monomer mass concentration on the relative radiopacity（ RXO）,double bond conversion（ DC）,volumetric shrinkage（ VS）,water sorption（ WS）,solubility（ SL） and mechanical properties of the TIMEC-containing resin formulations were investigated. It is found that,as compared with the control resin,namely the Bis-GMA/TEGDMA without TIMEC,the TIMEC-containing resins are of higher RXO and lower WS,SL and VS. Moreover,although the DC and mechanical properties of part resins are moderately reduced,the resin containing 20% TIMEC is excellent in each index,specifically,its RXO,DC,VS,WS,SL,flexural modulus and flexural strength are 113%,57. 5%,6. 41%,2. 65%,0. 49%,3 038 MPa and 123. 1 MPa respectively,all of which are superior to those of the control resin except the DC. The results show that TIMEC is of potential application prospects.

关 键 词：牙科树脂 甲基丙烯酸酯单体 物理化学性能 造影剂 X射线阻射性 

分 类 号：TB332[一般工业技术—材料科学与工程] R783.1[医药卫生—口腔医学]