针刺五脏俞加膈俞配神门穴治疗女性更年期失眠临床研究  

Acupuncture at back-shu points of five zang, Geshu(BL 17) and Shenmen(HT 7) for the treatment of menopausal insomnia

作　　者：李欧静 王凡[2] LI Oujing. WANG Fan(1.Department of TCM. Asian Sports Village Community Health Service Center. Bei.jing 100101. China： 2Department of Acupuncture and Moxibustion. Beijing Tibetan Hospital of China Tibetology Research Center. Beijing 10002)

机构地区：[1]北京市朝阳区亚运村社区卫生服务中心中医科,北京100101 [2]中国藏学研究中心北京藏医院针灸科,北京100029

出　　处：《中国针灸》2018年第5期469-472,共4页Chinese Acupuncture & Moxibustion

摘　　要：目的:比较针刺五脏俞加膈俞配神门穴与常规西药治疗女性更年期失眠的临床疗效差异。方法:将128例女性更年期失眠患者随机分为观察组与对照组,每组64例。其中观察组4例患者退出,对照组2例患者退出。观察组针刺肺俞、心俞、肝俞、脾俞、肾俞、膈俞、神门穴,每日1次,每治疗5 d休息2 d。对照组每晚睡前口服西药阿普唑仑0.4 mg或0.8 mg。两组均治疗3周为一疗程,连续治疗3个疗程。于治疗前和结束后30 d,观察两组患者匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)和血清雌二醇(estradiol,E_2)、卵泡刺激素(follicle-stimulating hormone,FSH)、促黄体生成素(luteinizing hormone,LH)水平,并于治疗结束后30 d进行疗效评价。结果:治疗结束后30 d两组患者PSQI各项指标评分及总分均低于治疗前(均P<0.05),且观察组均低于对照组(均P<0.05);治疗结束后30 d两组患者E_2水平高于治疗前、FSH及LH水平低于治疗前(均P<0.05),且观察组均优于对照组(均P<0.05);观察组总有效率为98.3%(59/60),优于对照组的95.2%(59/62,P<0.05)。结论:针刺五脏俞加膈俞配神门穴治疗女性更年期失眠有较好的疗效,优于西药阿普唑仑治疗。Objective To compare the clinical efficacy differences between acupuncture at back-shu points of five zang,Geshu（BL 17）, Shenmen（HT 7） and regular medication for the treatment of menopausal insomnia. Methods A total of 128 female patients of menopausal insomnia were randomly divided into an observation group and a control group, 64 cases in each one. Four patients in the observation group and 2 patients in the control group dropped out during the treatment. The patients in the observation group were treated with acupuncture at Feishu（BL 13）, Xinshu（BL 15）, Pishu（BL 20）, Ganshu（BL 18）, Shenshu（BL 23）,Geshu（BL 17） and Shenmen（HT 7）, once a day, and there was an interval of 2 days between every 5 days of treatment. The patients in the control group were treated with oral administration of alprazolam（0.4 mg or 0.8 mg） before sleep. Three-week treatment was taken as one course, and totally three courses were given in the two groups. Pittsburgh sleep quality index（PSQI）, levels of estradiol（E2）, follicle-stimulating hormone（FSH） and luteinizing hormone（LH） were observed before treatment and 30 days after treatment;the efficacy was evaluated 30 days after treatment. Results Each item score and total score of PSQI 30 days after treatment were lower than those before treatment in the two groups（all P〈0.05）, the scores in the observation group were lower than those in the control group（all P〈0.05）. The levels of E2 30 days after treatment were higher than those before treatment in the two groups（both P〈0.05）, but the level of FSH and LH 30 days after treatment were lower than those before treatment in the two groups; the level in the observation group was superior to that in the control group（all P〈0.05）. The total effective rate was 98.3%（59/60） in the observation group, which was better than 95.2%（59/62） in the control group（P〈0.05）. Conclusion Acupuncture at Feishu（BL 13）, Xinshu（BL 15）, Ganshu（BL 18）, Pishu（BL 20

关 键 词：更年期失眠 女性 针刺 五脏俞 穴 膈俞 穴 神门 阿普唑仑 匹兹堡睡眠质量指数 雌二醇 卵泡刺激素 

分 类 号：R246.3[医药卫生—针灸推拿学]