补肾助孕汤联合雌孕激素治疗宫腔粘连分离术后患者临床观察  

Clinical Observation of Bushen Zhuyun Tang Combined with Estrogen and Progesterone for Patients after Separation of Intrauterine Adhesions

作　　者：郑小平 高微微 陆海英 王碧芬 ZHENG Xiaoping,GAO Weiwei,LU Haiying,WANG Bifen

机构地区：[1]舟山市普陀区中医院,浙江舟山316100

出　　处：《新中医》2018年第5期131-134,共4页New Chinese Medicine

摘　　要：目的:观察补肾助孕汤联合雌孕激素辅助治疗宫腔粘连分离术患者的临床效果。方法:纳入96例行宫腔粘连分离术患者,随机分为治疗组和对照组各48例。2组均在宫腔镜下行宫腔粘连分离术,对照组术后予雌孕激素治疗,治疗组予补肾助孕汤联合雌孕激素治疗。比较2组临床疗效,记录患者妊娠及宫腔粘连复发情况,检测子宫内膜厚度及子宫动脉血流阻力指数(RI)和子宫动脉搏动指数(PI)。结果:治疗组总有效率93.75%,对照组总有效率75.00%,2组比较,差异有统计学意义(P<0.05)。治疗组妊娠率62.50%,高于对照组的39.58%(P<0.05)。治疗组宫腔粘连复发率12.50%,低于对照组的31.25%(P<0.05)。治疗前,2组子宫内膜厚度及PI、RI比较,差异均无统计学意义(P>0.05)。治疗后,2组子宫内膜厚度均增加,RI和PI均减少,差异均有统计学意义(P<0.05);治疗组子宫内膜厚度大于对照组,RI和PI低于对照组,差异均有统计学意义(P<0.05)。结论:宫腔粘连分离术后应用补肾助孕汤联合雌孕激素治疗可提高妊娠率,降低宫腔粘连复发率,改善子宫血液循环,促进子宫内膜恢复。Objective：To observe the clinical effect of Bushen Zhuyun tang combined with estrogen and progesterone for patients after separation of intrauterine adhesions. Methods： Selected 96 cases of patients with separation of intrauterine adhesions,and divided them into the treatment group and the control group randomly,48 cases in each group. Both groups received hysteroscopic separation of intrauterine adhesions,and the control group was given estrogen and progesterone for treatment, while the treatment group was given Bushen Zhuyun tang combined with estrogen and progesterone for treatment. Compared the clinical effect of both groups, recorded the pregnancy rate and the recurrence of intrauterine adhesions of patients, and detected the endometrial thickness, blood flow resistance index（RI） of the uterine artery and pulsatility index of the uterine artery（PI）. Results：The total effective rate was 93.75% in the treatment group and 75.00% in the control group,difference being significant（P〈0.05）. The pregnancy rate was 62.50% in the treatment group,being higher than 39.58% in the control group（P〈0.05）. The recurrence rate was 12.50% in the treatment group, being lower than31.25% in the control group（P〈0.05）. Before treatment,comparing the endometrial thickness,RI and PI of both groups,there were no significant differences being found（P〈0.05）. After treatment,the endometrial thickness of both groups was increased,and RI and PI were decreased,differences being significant（P〈0.05）. The endometrium of the treatment group was thicker than that of the control group, and RI and PI were lower than those of the control group, differences being significant（P〈0.05）. Conclusion：The application of Bushen Zhuyun tang combined with estrogen and progesterone after separation of intrauterine adhesions can increase the pregnancy rate,reduce the recurrence rate of intrauterine adhesions,improve the uterine blood circulation and promote the recovery of the thickness of endometrium.

关 键 词：宫腔粘连分离术 补肾助孕汤 雌激素 孕激素 子宫内膜 子宫动脉血流阻力指数(RI) 子宫动脉搏动指数(PI) 

分 类 号：R713[医药卫生—妇产科学]