铜陵市老年人呼吸道感染病原体调查  

Investigation on pathogens of respiratory tract infection in elderly people in Tongling City

作　　者：汪锐 田静 陈自武[1] 林成 汪伟 潘晓龙[2] 钱泽平 黄丽 焦瑞宝[2] WANG Rui;TIAN Jing;CHEN Ziwu;LIN Cheng;WANG Wei;PAN Xiaolong;QIAN Zeping;HUANG Li;JIAO Ruibao(Tongling Chinese Medicine Hospital, Tongling ,Anhui 244000, China;Tongling People＇s Hospital, Tongling ,Anhui 244000, China;Tongling Maternal and Child Health Hospital, TonglinE, Anhui 244000, China;Tongling Municipal Hospital, Tongling ,Anhui 244000, China)

机构地区：[1]安徽省铜陵市中医医院,244000 [2]安徽省铜陵市人民医院,244000 [3]安徽省铜陵市妇幼保健院,244000 [4]安徽省铜陵市立医院,244000

出　　处：《检验医学与临床》2018年第10期1387-1389,1392,共4页Laboratory Medicine and Clinic

基　　金：安徽省铜陵市基层临床医学实验室科技计划项目(2015NS 12)

摘　　要：目的探讨老年呼吸道感染患者的病原体分布,为临床防治提供参考。方法收集铜陵市4家三甲医院747例住院老年呼吸道感染患者并进行痰细菌培养,采用间接免疫荧光法检测血清11项呼吸道病原体免疫球蛋白M(IgM)抗体。结果 747例老年患者,男507例(67.87%),女240例(32.13%),男、女2组病原体阳性率分别为27.22%和26.25%,差异无统计学意义(χ~2=0.078,P>0.05);70~<80岁年龄组患者病原体阳性率为22.23%,低于其他各年龄组,差异有统计学意义(χ~2=8.639,P<0.05);痰细菌培养57例阳性,血清学抗体非细菌性病原体153例阳性,其中9例同时合并细菌和非细菌性病原体感染,阳性率为7.62%和20.48%,差异有统计学意义(χ~2=51.063,P<0.05);细菌感染前3位是肺炎克雷伯菌、鲍曼不动杆菌、铜绿假单胞菌,非细菌性病原体前3位是肺炎支原体、肺炎衣原体、流感病毒B型。结论老年人呼吸道感染的非细菌性病原体阳性率明显高于细菌感染,临床治疗前需检测病原微生物,避免滥用抗菌药物。Objective To investigate pathogens distribution in elderly patients with respiratory tract infections,and providing references for clinical prevention and treatment.Methods A total of 747 cases of elderly patients with respiratory tract infections in four tertiary referral hospitals of Tongling were selected,sputum bacterial culture was performed with all patients.A total of 11 serological IgM antibody of respiratory pathogens were detected by indirect immunofluorescence.Results A total of 507 male and 240 female constituted747 cases,the ratio was 67.87% and 32.13% respectively.Positive rate of pathogens was 27.22% in male group and 26.25%in female group.The comparison between the two groups revealed that（χ~2=0.078）,the difference was not statistically significant（P〈0.05）;the experiment was grouped by age,positive rate of pathogens in 70-80 years old age group were 22.23%,which was lower than other groups（χ~2=8.639）,the difference was statistically significant（P〈0.05）.A total of 57 cases sputum bacterial culture were positive,positive cases of serological nonbacterial pathogen antibodies were 153,including 9 cases with double infection of bacteria and nonbacterial pathogens.The positive rate was 7.62% and 20.48% respectively（χ~2=51.063）,the difference was statistically significant（P〈0.05）;the top three bacteria pathogens were klebsiella pneumoniae,acinetobacter baumannii,pseudomonas aeruginosa,the top three nonbacteria pathogens were pneumonia mycoplasma,pneumonia chlamydia and type B influenza virus.Conclusion The positive rate of bacterial pathogens in elderly patients with respiratory tract infections was obviously higher than that of nonbacterial pathogens,so in order to avoid abusing of antimicrobial agents,it′s important to find out the pathogenic microorganism at first.

关 键 词：呼吸道感染 非细菌性病原体 免疫球蛋白M 

分 类 号：R562[医药卫生—呼吸系统]