新生儿高胆汁酸血症的高危因素分析  

Analysis of risk factors of hypercholanaemia in newly born neonates

作　　者：王克煊[1] 刘俊燕[1] 李燕[1] WANG Kexuan;L IU Junyan;LI Yan(Department of Neonatology , Binzhou Medical University Hospital , Binzhou, Shangdong 256603, Chin)

机构地区：[1]滨州医学院附属医院新生儿科,山东滨州256603

出　　处：《检验医学与临床》2018年第10期1403-1404,1407,共3页Laboratory Medicine and Clinic

摘　　要：目的探讨新生儿高胆汁酸血症的高危因素,以指导临床的预后判断及治疗。方法选择该院864例新生儿(其中高胆汁酸血症患儿120例)及其母孕期的病历资料,并对新生儿高胆汁酸血症的影响因素进行统计,采用R语言统计学方法进行分析,分析高危因素且计算回归方程。结果孕妇妊高征、高胆汁酸血症为患儿高胆汁酸血症的高危因素并呈正相关关系(P<0.05);出生体质量与患儿高胆汁酸血症呈负相关关系(P<0.05)。结论孕期妊高征、高胆汁酸血症均可导致新生儿高胆汁酸血症,且在一定程度上反映胎盘功能,可对患儿的预后判断具有临床指导意义。Objective To investigate the risk factors of hypercholanaemia in newly born neonates through retrospective analysis,in an attempt to guide prognosis and treatment of the condition.Methods Medical records of 864 newly born neonates（including 120 cases with hypercholanaemia）and their mothers during pregnancy were retrospectively analyzed,and the possible influencing factors that might cause Hypercholanaemia were summarized.The resulting data was analyzed by using the R-based statistical method,so as to find out the high risk factors and calculate the regression equation.Results Analysis showed that hypertension and hypercholanae-mia of pregnancy were positively correlated with hypercholanaemia in newly born neonates;while birth weight was negatively correlated with hypercholanaemia in newly born neonates.Conclusion Both hypertension and hypercholanaemia of pregnancy could lead to hypercholanaemia in newly born neonates.However,the condition at birth could to a certain extent reflect the placental function of the newborns,which might be essential in guiding the prognosis.

关 键 词：新生儿 高胆汁酸血症 高危因素 

分 类 号：R722[医药卫生—儿科]