黛力新对COPD住院患者伴焦虑抑郁的疗效观察  

Observation on efficacy of Deanxit on anxiety and depression in hospitalized COPD patients

作　　者：樊荣兴 FAN Rong- xing.(Department of Respiratory Medicine, Sihui People＇ s Hospital, Sihui 526200, Chin)

机构地区：[1]四会市人民医院呼吸内科,526200

出　　处：《中国实用医药》2018年第13期93-95,共3页China Practical Medicine

摘　　要：目的观察氟哌噻吨美利曲辛片(黛力新)对慢性阻塞性肺疾病(COPD)伴焦虑抑郁住院患者的疗效。方法 80例COPD伴焦虑抑郁住院患者,按照疗法不同分为常规组与观察组,每组40例。常规组采用常规治疗,观察组在常规治疗基础上加用黛力新治疗,对比两组临床疗效、治疗前后的动脉血气指标[血氧饱和度(Sp O_2)、血氧分压(Pa O_2)、动脉血二氧化碳分压(Pa CO_2)、p H]和心理状态评分[焦虑自评量表(SAS)及抑郁自评量表(SDS)评分]。结果常规组的总有效率为67.5%,观察组的总有效率为90.0%;观察组总有效率高于常规组,差异有统计学意义(P<0.05)。治疗前两组动脉血气指标比较差异无统计学意义(P>0.05);治疗后观察组Sp O_2、Pa O_2、p H均高于常规组,Pa CO_2低于常规组,差异有统计学意义(P<0.05)。治疗前两组SAS及SDS评分比较差异无统计学意义(P>0.05);治疗后观察组SAS、SDS评分均低于常规组,差异有统计学意义(P<0.05)。结论黛力新对COPD住院患者伴焦虑抑郁的疗效显著,可明显改善患者的动脉血气与焦虑抑郁心理,值得推行。Objective To observe the efficacy of flupentixol and melitracen tablets（Deanxit） on anxiety and depression in hospitalized chronic obstructive pulmonary disease（COPD） patients. Methods A total of 80 hospitalized COPD patients with anxiety and depression were divided by different treatment methods into conventional group and observation group, with 40 cases in each group. The conventional group received conventional therapy, and the observation group received Deanxit for treatment on the basis of the conventional group. Comparison were made on clinical efficacy, arterial blood gas index [blood oxygen saturation（Sp O_2）, blood oxygen partial pressure（Pa O_2）, arterial blood carbon dioxide pressure（Pa CO_2）, p H], psychological state score [self-rating anxiety scale（SAS） and self-rating depression scale（SDS） score] before and after treatment between the two groups. Results The conventional group had total effective rate as 67.5%, which was 90.0% in the observation group. The observation group had higher total effective rate than the conventional group, and the difference was statistically significant（P〈0.05）. Before treatment, both groups had no statistically significant difference in arterial blood gas index（P〉0.05）. After treatment, the observation group had higher Sp O_2, Pa O_2, p H than conventional group, and lower Pa CO_2 than conventional group. Their difference was statistically significant（P〈0.05）. Before treatment, both groups had no statistically significant difference in SAS and SDS score（P〉0.05）. After treatment, the observation group had lower SAS and SDS score than conventional group, and the difference was statistically significant（P〈0.05）. Conclusion Deanxit shows remarkable efficacy on hospitalized COPD patients with anxiety and depression, and it can obviously improve arterial blood gas and anxiety and depression state. It is worthy of implementation.

关 键 词：氟哌噻吨美利曲辛片 慢性阻塞性肺疾病 焦虑抑郁 

分 类 号：R563.9[医药卫生—呼吸系统] R749.4[医药卫生—内科学]