雷公藤多苷联合激素治疗中度活动型系统性红斑狼疮的临床效果分析  

Clinical effect of tripterygium glycosides combined with hormone in the treatment of moderate active systemic lupus erythematosus

作　　者：王萍[1] WANG Ping.(Department of Rheumatism Immunity, Dalian Friendship Hospital, Dalian 116001, China)

机构地区：[1]大连市友谊医院风湿免疫科,116001

出　　处：《中国实用医药》2018年第13期99-100,共2页China Practical Medicine

摘　　要：目的探讨雷公藤多苷联合激素治疗中度活动型系统性红斑狼疮的临床效果。方法 80例中度活动型系统性红斑狼疮患者,随机分为试验组和对照组,每组40例。对照组在常规治疗的基础上加用醋酸泼尼松治疗,试验组在对照组基础上使用雷公藤多苷治疗,比较两组患者治疗后的临床治疗效果。结果试验组的临床有效率为95.0%,对照组的临床有效率为80.0%,试验组临床有效率高于对照组,差异具有统计学意义(P<0.05)。结论使用雷公藤多苷联合激素治疗中度活动型系统性红斑狼疮临床效果显著,值得在临床推广。Objective To discuss the clinical effect of tripterygium glycosides combined with hormone in the treatment of moderate active systemic lupus erythematosus. Methods A total of 80 patients with moderate active systemic lupus erythematosus were randomly divided into experimental group and control group, with 40 cases in each group. The control group received prednisone acetate on the basis of conventional therapy, and the experimental group received tripterygium glycosides on the basis of the control group. The clinical treatment effect after treatment between two groups was compared. Results The experimental group had clinical effective rate as 95.0%, which was 80.0% in the control group. The experimental group had higher clinical efficacy than the control group, and the difference was statistically significant（P〈0.05）. Conclusion Combination of tripterygium glycosides and prednisone acetate shows remarkable clinical effect in treating moderate active systemic lupus erythematosus, and it is worthy of clinical promotion.

关 键 词：雷公藤多苷 醋酸泼尼松 系统性红斑狼疮 

分 类 号：R593.241[医药卫生—内科学]