关节腔内注射不同浓度右美托咪定复合罗哌卡因对老年骨科患者膝关节镜术后镇痛效果  

Intra-articular injection of different concentration of dexmedetomidine combined with ropivacaine on analgesic effect of knee arthroscopy in elderly patients in the department of orthopedics

作　　者：潘春英[1] 许旭东[1] 张爱萍[1] 郦惠芳[1] 霍燕华 瞿玉兴[1] PAN Chunying;XU Xudong;ZHANG Aiping;LI Huifang;HUO Yanhua;QU Yuxing(Department of Anesthesiology Changzhou traditional Chinese Medicine Hospital Affiliated to Nanjing University of Chinese Medicine,Changzhou 213000,China)

机构地区：[1]南京中医药大学附属常州市中医医院麻醉科,江苏常州213000

出　　处：《实用医学杂志》2018年第10期1702-1704,共3页The Journal of Practical Medicine

基　　金：江苏省中医药局科技项目(编号:LZ11137)

摘　　要：目的探讨不同浓度右美托咪定+罗哌卡因用于老年骨科患者膝关节镜术后的镇痛效果。方法选取72例于2016年2月至2017年9月在本院择期实施膝关节镜手术治疗的患者分为4组,术后分别给予不同浓度右美托咪定+罗哌卡因,对比各组镇痛效果及不良反应。结果在镇痛持续时间上,C、D组长于A、B组;4组术后不良反应发生率比较差异也无显著性(P>0.05);术后1、3、6、10、16、24h,C、D组VAS评分均显著低于A、B组(P<0.05)。结论右美托咪定+罗哌卡因用于膝关节镜术后可有效提高镇痛效果,0.50μg/kg为右美托咪定的最佳浓度。Objective To investigate the analgesic effect of different concentrations of medetomidine andropivacaine on knee arthroscopy in elderly patients in the orthopedics department. Methods 72 patients were di-vided into 4 groups,and from February 2016-September 2017,different concentrations of dexmedetomidin andropivacaine were given to the patients after the operation,and compared the analgesic effects and adverse reactionsof each group. Results The duration of analgesia in groups C and D were longer than group A and B and therewere significant differences in the amount of fentanyl in the 4 groups after 24h（F=79.633,P〈0.05）and therewas no significant difference in the incidence of adverse reactions between the 4 groups（P〉0.05）;1,3,6,10,16,24h after operation,The VAS scores in group C and D were significantly lower than those in group A andB（P〈0.05）. Conclusion Dexmedetomidine plus ropivacaine can effectively improve the analgesic effect afterknee arthroscopy,0.50g/kg was the best concentration of dexmedetomidin.

关 键 词：膝关节镜手术 镇痛 不良反应 

分 类 号：R614[医药卫生—麻醉学]